Evidence map›Paper›PMID 41069815›Full record

ArticleFrontiers in public health2025

Global patterns and health impact of unintentional injuries among children and adolescents, 1990-2021.

Wei Wei, Wei Lyu, Yuchen Zhang

Abstract read
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Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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0cells of the map it votes in
5citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wei WeiZhengzhou College of Finance and Economics, Zhengzhou, China.
Wei LyuFaculty of Medicine and Health, Al-Farabi Kazakh National University, Almaty, Kazakhstan.
Yuchen ZhangHenan University of Technology, Zhengzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Summary: Unintentional injuries significantly threaten the health of children and adolescents globally. Annually, injuries result in approximately five million deaths worldwide, with around 12% occurring in children. This study investigates global trends in incidence, mortality, and disability-adjusted life years (DALYs) associated with unintentional injuries among children and adolescents from 1990 to 2021. Methods: We conducted an analysis of global unintentional injury incidence, mortality, and DALYs among individuals aged 0-19 years using data from the Global Burden of Disease (GBD) database. Incidence, mortality, and DALY rates per 100,000 population were calculated, accompanied by 95% uncertainty intervals (UI). Data from 204 countries and territories were stratified by age, sex, and geographic region. Trend analyses utilized Joinpoint regression modeling to calculate annual percentage changes (APC) and log-transformed linear regression to estimate the estimated annual percentage change (EAPC). Projections of injury burden through 2035 were generated using Bayesian age-period-cohort (BAPC) modeling. Findings: Globally, in 2021, unintentional injuries in children and adolescents resulted in 157,808,979 cases (95% UI: 138,280,367-179,472,942), 305,596 deaths (95% UI: 240,004-365,146), and 28,410,167 DALYs (95% UI: 23,100,433-33,513,238). Among the five socio-demographic index (SDI) regions, the low-middle SDI region exhibited the most significant decrease in injury incidence. Regionally, from 1990 to 2021, the Caribbean experienced the largest relative increase in injury incidence (EAPC 0.25, 95% CI: -0.60 to 1.11). At the country level, India reported the highest absolute number of cases (24,115,574; 95% UI: 21,137,414-27,296,091). BAPC modeling predicts a continued reduction in the global burden of unintentional injuries up to 2035. Interpretation: Global trends demonstrate declining incidence, mortality, and DALYs associated with unintentional injuries among children and adolescents. Comprehensive epidemiological insights are critical for enhancing targeted prevention strategies and control measures to mitigate injury burden in this vulnerable population.

Indexed as

Accidental InjuriesGlobal HealthWounds and InjuriesAdolescentChildChild, PreschoolDisability-Adjusted Life YearsFemaleGlobal Burden of DiseaseHumansIncidenceInfantInfant, NewbornMaleQuality-Adjusted Life YearsYoung AdultBAPC prediction modelchildren and adolescentsDALYs - disability-adjusted life yearsincidencemortalityunintentional injuries

Identifiers

PMID41069815
PMCPMC12504300

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.