Evidence map›Paper›PMID 41069797›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)

Speech and language features as indicators of neuropsychiatric symptoms in a memory clinic population.

Zampeta-Sofia Alexopoulou, Elisa Mallick, Johannes Tröger, Daphne Ter Huurne, Nina Possemis, Valeria Manera, Inez Ramakers, Alexandra König

Abstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zampeta-Sofia AlexopoulouCoBTeK (Cognition-Behaviour-Technology) Research Lab Université Côte d'Azur Nice France.
Elisa Mallickki:elements GmbH Saarbrücken Germany.
Johannes Trögerki:elements GmbH Saarbrücken Germany.
Daphne Ter HuurneDepartment of Psychiatry and Psychology Maastricht University Medical Centre+ (MUMC+) Maastricht the Netherlands.
Nina PossemisAlzheimer Center Limburg Department of Psychiatry & Neuropsychology Mental Health and Neuroscience Research Institute Maastricht University Maastricht the Netherlands.
Valeria ManeraCoBTeK (Cognition-Behaviour-Technology) Research Lab Université Côte d'Azur Nice France.
Inez RamakersAlzheimer Center Limburg Department of Psychiatry & Neuropsychology Mental Health and Neuroscience Research Institute Maastricht University Maastricht the Netherlands.
Alexandra KönigCoBTeK (Cognition-Behaviour-Technology) Research Lab Université Côte d'Azur Nice France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNeuropsychiatric symptoms (NPSs) are early hallmarks of neurocognitive disorders (NCDs). Speech alterations might indicate both cognitive and behavioral changes in NCDs, aiding in diagnosis and disease monitoring. This study examined associations between automatically extracted speech/language features and NPS severity.

methodsA total of

resultsFeatures correlated significantly with NPSs. Indicatively, depression correlated with local jitter ( DISCUSSION: Speech analysis offers a promising tool for evaluating NPSs in NCDs. Highlights: We found links between neuropsychiatric symptom (NPS) severity and speech markers in memory clinic patients.Temporal markers positively correlated with the presence and severity of agitation.Depression was positively correlated with voice instabilities.Anxiety was negatively associated with metrics of lexical diversity.Speech analysis provides an objective tool to assess NPSs in subjective cognitive decline and mild cognitive impairment patients.

Indexed as

agitationanxietyapathydepressiondigital biomarkersmild cognitive impairmentneurocognitive disordersneuropsychiatric symptomsspeech analysisspeech biomarkers

Identifiers

PMID41069797
PMCPMC12505190

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.