Evidence map›Paper›PMID 41069754›Full record

ArticleClinical case reports2025

Isotretinoin-Associated Myopathy With Normal Creatine Kinase (CK) Levels: EMG-Based Diagnosis at Low Dose-A Case Report.

Mehran Mahyar, Roya Jahanbazi, Ali Khorram, Soheil Shahramirad, Mohammadreza Vataniman

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mehran MahyarDepartment of Neurology, Faculty of Medicine Hormozgan University of Medical Sciences Bandar Abbas Iran.ORCID https://orcid.org/0009-0005-0065-042X
Roya JahanbaziDepartment of Medical Sciences Yazd.C., Islamic Azad University Yazd Iran.ORCID https://orcid.org/0009-0003-5828-7390
Ali KhorramStudent Research Committee, Faculty of Medicine Hormozgan University of Medical Sciences Bandar Abbas Iran.ORCID https://orcid.org/0009-0005-8589-887X
Soheil ShahramiradDepartment of Medical Sciences Sha.C., Islamic Azad University Shahrood Iran.ORCID https://orcid.org/0009-0005-0555-2466
Mohammadreza VatanimanStudent Research Committee, Faculty of Medicine Hormozgan University of Medical Sciences Bandar Abbas Iran.ORCID https://orcid.org/0009-0007-5624-2382

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Isotretinoin can cause toxic myopathy even at low doses with normal CK levels; proximal muscle weakness may be the only sign. EMG is essential for diagnosis, emphasizing the need for clinical vigilance and personalized assessment in patients with unexplained muscle symptoms on isotretinoin.

Indexed as

adverse effectschemically inducedcreatine kinase (CK)electromyography (EMG)isotretinoinmyopathy

Identifiers

PMID41069754
PMCPMC12504136

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.