ArticleJournal of advanced veterinary and animal research2025
Anti-methanogenic effect of phytogenic extract of
Article in Journal of advanced veterinary and animal research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
Objectives: This study aimed to assess the anti-methanogenic potential of Materials and Methods: Phytochemicals from Results: Selected phytochemicals, including pterygospermin, exhibited promising drug-likeness based on Lipinski's rule of five and absorption, distribution, metabolism, excretion, and toxicology properties. Pterygospermin demonstrated the highest binding affinity to the MCR enzyme's active site, with interactions including Pi-sulfur (Phe443), Pi-alkyl (Val482, Leu320, and Met324), Pi-Pi stacking (Phe330), and van der Waals forces (Tyr333 and Ser325). Conclusion: Pterygospermin shows potential as a competitive inhibitor of the MCR enzyme, providing a sustainable approach to mitigate methane emissions in livestock and contribute to global greenhouse gas reduction efforts.
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