Evidence map›Paper›PMID 41069686›Full record

ArticleUrology case reports2025

Primary bladder signet ring cell adenocarcinoma in a young male with Lynch Syndrome.

James Um, Aidan Kennedy, Christopher D Jaeger, Nikta Rezakahn Khajeh, Paul Alan Horning, Reenal Patel, Kanika Arora, Adam J Gadzinski

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Urology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

James UmDepartment of Urology, Corewell Health William Beaumont University, Royal Oak, MI, United States of America.
Aidan KennedyDepartment of Urology, Corewell Health William Beaumont University, Royal Oak, MI, United States of America.
Christopher D JaegerDepartment of Urology, Corewell Health William Beaumont University, Royal Oak, MI, United States of America.
Nikta Rezakahn KhajehDepartment of Urology, Corewell Health William Beaumont University, Royal Oak, MI, United States of America.
Paul Alan HorningDepartment of Urology, Corewell Health William Beaumont University, Royal Oak, MI, United States of America.
Reenal PatelDepartment of Urology, Corewell Health William Beaumont University, Royal Oak, MI, United States of America.
Kanika AroraDepartment of Urology, Corewell Health William Beaumont University, Royal Oak, MI, United States of America.
Adam J GadzinskiDepartment of Urology, Corewell Health William Beaumont University, Royal Oak, MI, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 32-year-old male with Lynch Syndrome and a history of colon cancer status post total proctocolectomy was found to have invasive high-grade carcinoma with signet ring cell morphology on tissue sampling of the bladder neck following transurethral resection of a bladder tumor (TURBT). The patient subsequently underwent an open cystoprostatectomy and completion proctectomy. Final pathology of the prostate, bladder, and bladder augment confirmed the diagnosis of signet ring cell adenocarcinoma (SRCC) of the bladder. Given its rarity, this case illustrates the challenges of managing an aggressive bladder cancer and underscores the importance of considering appropriate screening strategies in high-risk populations.

Indexed as

Bladder cancerCase reportLynch syndromeSignet ring cell carcinoma

Identifiers

PMID41069686
PMCPMC12505680

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.