Evidence map›Paper›PMID 41069573›Full record

ReviewCureus2025

Efficacy of Platelet-Rich Plasma as an Adjunct to Hair Transplantation: A Systematic Review.

Sasipaka Sindhusen, Weeratian Tawanwongsri, Chime Eden

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sasipaka SindhusenDivision of Dermatology, Bhumibol Adulyadej Hospital, Bangkok, THA.
Weeratian TawanwongsriDivision of Dermatology, Department of Internal Medicine, School of Medicine, Walailak University, Nakhon Si Thammarat, THA.
Chime EdenDivision of Dermatology, Jigme Dorji Wangchuck National Referral Hospital, Thimphu, BTN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hair transplantation is a well-established treatment for androgenetic alopecia (AGA), yet the long-term success of grafts can vary due to multiple influencing factors. Platelet-rich plasma (PRP) has gained attention as a potential adjunctive therapy aimed at enhancing graft survival and promoting hair regrowth. This systematic review evaluated the clinical efficacy of PRP when used alongside hair transplantation. A comprehensive search of Scopus, MEDLINE (via PubMed), and DOAJ was conducted from database inception to June 2025. Eligible studies were prospective clinical trials with control groups that investigated the use of PRP in patients undergoing hair transplantation. Three studies, including two randomized controlled trials and one non-randomized controlled study, met the inclusion criteria, encompassing a total of 217 participants. Across all studies, the addition of PRP was associated with improved outcomes, including increased hair density, enhanced follicle survival, and earlier initiation of hair growth. However, notable heterogeneity was observed in PRP preparation methods, treatment protocols, and outcome measures. Furthermore, none of the studies employed standardized evaluation tools or trichoscopic analysis, limiting the consistency and comparability of findings. While the current evidence suggests that PRP may offer clinical benefits as an adjunct to hair transplantation, further high-quality randomized trials with standardized protocols and long-term follow-up are needed to establish its therapeutic role with greater confidence.

Indexed as

androgenetic alopeciahair transplantationplatelet-rich plasmascalptreatment outcome

Identifiers

PMID41069573
PMCPMC12506585

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.