Evidence map›Paper›PMID 41069497›Full record

ArticleJournal of public health in Africa2025

Pathogenesis of rabies in a pregnant HIV immune-compromised woman in Zambia: A case report.

Martin Nyahoda, Mukatimui K Munalula, Agripa Lungu, Walter Muleya, Selia Ng'anjo, Willies Silwimba, Chrispin Mwando, Joyce N Shampile

Abstract readCase Reports
In one paragraph

Article in Journal of public health in Africa, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Martin NyahodaDepartment of Disease Control, School of Veterinary Medicine, University of Zambia, Lusaka, Zambia.ORCID https://orcid.org/0000-0003-2069-7434
Mukatimui K MunalulaUniversity Teaching Hospitals, Women and Newborn Hospital, Lusaka, Zambia.ORCID https://orcid.org/0000-0002-3460-983X
Agripa LunguUniversity Teaching Hospitals, Women and Newborn Hospital, Lusaka, Zambia.ORCID https://orcid.org/0000-0003-1248-8982
Walter MuleyaDepartment of Disease Control, School of Veterinary Medicine, University of Zambia, Lusaka, Zambia.ORCID https://orcid.org/0000-0001-8874-3965
Selia Ng'anjoUniversity Teaching Hospitals, Women and Newborn Hospital, Lusaka, Zambia.ORCID https://orcid.org/0000-0001-6827-7610
Willies SilwimbaUniversity Teaching Hospitals, Women and Newborn Hospital, Lusaka, Zambia.ORCID https://orcid.org/0009-0001-6752-4656
Chrispin MwandoUniversity Teaching Hospitals, Women and Newborn Hospital, Lusaka, Zambia.ORCID https://orcid.org/0009-0009-9843-1610
Joyce N ShampileUniversity Teaching Hospitals, Women and Newborn Hospital, Lusaka, Zambia.ORCID https://orcid.org/0009-0009-8183-8174

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rabies is a fatal neglected tropical zoonotic disease caused by neurotropic viruses of the genus Lyssavirus in the family Rhabdoviridae. We report the disease progression in a 30-year-old woman, in her eighth pregnancy, living with human immunodeficiency virus (HIV) on antiretroviral therapy (ART), who presented with neurological symptoms including aggression, restlessness, fever and vomiting 20 days following rabies exposure through multiple dog bites on the face and upper limbs. She had received a 4-dose regimen of rabies post-exposure prophylaxis (PEP), starting 2 days after exposure, with subsequent doses given 3 and 7 days later, while the 4th dose was administered 20 days after exposure. Wound washing was not performed, and rabies immunoglobulin was not administered as recommended by the World Health Organization for category 3 exposures. The disease rapidly progressed to rabies encephalitis, leading to death within 6 days of admission. Reverse transcriptase polymerase chain reaction (RT-PCR) performed on cerebral spinal fluid (

Indexed as

HIVpathogenesispregnantrabiesZambia

Identifiers

PMID41069497
PMCPMC12505786

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.