Evidence map›Paper›PMID 41069441›Full record

ArticleJournal of otology2025

Otolith Degeneration with Aging: Insights from Video Ocular Counter-Roll (vOCR) Assessment.

Melissa Castillo-Bustamante, Jorge Madrigal, Elizabeth Andalón-Dueñas, Johanna Marcela Vanegas, Ireri Espinoza

Abstract read
In one paragraph

Article in Journal of otology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Unveiling Otolith Mystery: Contemporary Testing Approaches and Their Clinical Significance.World journal of otorhinolaryngology - head and neck surgery · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Melissa Castillo-BustamanteSchool of Health Sciences, Universidad Pontificia Bolivariana, Street 1ª 70-01, Medellín, Colombia.
Jorge MadrigalFacultad Mexicana de Medicina, Universidad La Salle México. Ciudad de México, México.
Elizabeth Andalón-DueñasCentro de Vértigo y Mareo. Guadalajara, México.
Johanna Marcela VanegasSchool of Health Sciences, Universidad Pontificia Bolivariana, Street 1ª 70-01, Medellín, Colombia.
Ireri EspinozaCentro de Vértigo y Mareo. Ciudad de México, México.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Vestibular assessments, such as the video ocular counter roll (vOCR) test, offer valuable insights into the interactions between age, otolith function, and vestibular performance. Objective: To analyze the relation between age and vOCR gains as a potential marker of age-related otolith degeneration. Methods: A total of 107 participants underwent vOCR testing. Descriptive statistics and simple linear regression analyses were conducted to explore the association between age and vOCR gains. Results were presented using regression coefficients, 95% confidence intervals, p-values, and R-squared values. Results: In the overall sample, statistically significant associations were observed between age and vOCR gains in both ears. For the right ear, vOCR gains decreased with increasing age (coefficient: -0.03; 95% CI: -0.05 to -0.01; p <0.001; R² = 0.08), while the left ear showed a slightly stronger association (coefficient: -0.04; 95% CI: -0.07 to -0.02; p < 0.001; R² = 0.12). These findings indicate a moderate age-related decline in otolith-mediated vestibular responses. Conclusion: vOCR gains appear to decline with age, reflecting potential age-related otolith degeneration. These results support the clinical value of vOCR as a non-invasive method to assess vestibular function and its changes across the lifespan.

Indexed as

Otolith degenerationvestibular disordersvestibular testingVideo ocular counter roll

Identifiers

PMID41069441
PMCPMC12510365

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.