ArticleFrontiers in neurology2025
Connectivity between supplementary motor complex and primary motor cortex: a dual-coil paired-pulse TMS study.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Unilateral contralesional versus bilateral repetitive transcranial magnetic stimulation for patients with post stroke dysphagia: a randomized controlled study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Trial
- Mechanisms of transcranial magnetic brain stimulation.Physiological reviews · 2026Review
- Motor Fiber Tract Changes Following iTBS Stimulation in a Basal Ganglia Stroke Patient: A Case Report.Clinical case reports · 2026Article
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Authors and funding
8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Dual-coil paired-pulse transcranial magnetic stimulation (ppTMS) has garnered interest for its potential in elucidating neural circuit dynamics. In this study, the dual-coil ppTMS was utilized to assess the effective connectivity between the supplementary motor complex (SMC) and the primary motor cortex (M1) in humans. A robust facilitatory connection between the SMC and M1 was observed, manifested as a 19% increase in mean peak-to-peak motor-evoked potentials following conditioning of SMC 7 ms prior to M1 stimulation. Importantly, the facilitatory influence of SMC was found in subjects who received conditioning stimulation 4 cm anterior to Cz, but not in those stimulated at 5 cm, 6 cm, or 7 cm. While previous work has focused on demonstrating important temporal dynamics for SMC-M1 plasticity, the present findings highlight a critical contribution of spatial specificity for the modulation of SMC-M1 circuitry.
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