Evidence map›Paper›PMID 41069125›Full record

ArticleChemistryOpen2026

Cyanoacetamidobetaine-A Zwitterionic Nitrile Derivative.

Pan Duan, Julia-Maria Hübner, Florian Puls, Vitaliy Romaka, Hans-Joachim Knölker, Michael Ruck

Abstract read
In one paragraph

Article in ChemistryOpen, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pan DuanFaculty of Chemistry and Food Chemistry, TUD Dresden University of Technology, 01062, Dresden, Germany.
Julia-Maria HübnerFaculty of Chemistry and Food Chemistry, TUD Dresden University of Technology, 01062, Dresden, Germany.ORCID https://orcid.org/0000-0003-2048-6629
Florian PulsFaculty of Chemistry and Food Chemistry, TUD Dresden University of Technology, 01062, Dresden, Germany.ORCID https://orcid.org/0000-0002-9735-1856
Vitaliy RomakaFaculty of Chemistry and Food Chemistry, TUD Dresden University of Technology, 01062, Dresden, Germany.
Hans-Joachim KnölkerFaculty of Chemistry and Food Chemistry, TUD Dresden University of Technology, 01062, Dresden, Germany.ORCID https://orcid.org/0000-0002-9631-5239
Michael RuckFaculty of Chemistry and Food Chemistry, TUD Dresden University of Technology, 01062, Dresden, Germany.ORCID https://orcid.org/0000-0002-2391-6025

Funding

German Research Foundation 247310070
6 · The paper itself

Abstract

Cyanoacetamidobetaine, or N-cyano-2-(trimethylammonio)acetaminide, is obtained from a reaction of sodium dicyanamide and betainium chloride in an aqueous solution after 4 h at 30 °C. By adding DCM, single-crystals suitable for diffraction experiments are obtained. The compound crystallizes in the monoclinic space group P2

Indexed as

betaine derivatecrystal structure analysisdensity functional theoryzwitterions

Identifiers

PMID41069125
PMCPMC13052206

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.