Evidence map›Paper›PMID 41068935›Full record

ArticleGenome biology2025

GIMIC: smoothed graph-image representation of microbiome samples induce an optimal distance.

Oshrit Shtossel, Yoram Louzoun

Abstract read
In one paragraph

Article in Genome biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Oshrit ShtosselDepartment of Mathematics, Bar-Ilan University, 52900, Ramat Gan, Israel.
Yoram LouzounDepartment of Mathematics, Bar-Ilan University, 52900, Ramat Gan, Israel. louzouy@math.biu.ac.il.

Funding

ISF grant 870/20
6 · The paper itself

Abstract

An essential tool in microbiome is the distance between samples. This serves to detect groups of similar samples. We have recently shown that combining the cladogram with the abundance of each microbe into a sorted normalized abundance tree can improve the accuracy of machine learning and differential analysis. We show that smoothing these tree-based images to produce GIMIC (Smoothed Graph IMages of the MICrobiome) leads to an interpretable visualization of microbiome sets and that the difference between the smoothed tree-based images is a better metric than the current state-of-the-art in a wide array of tasks.

Indexed as

Image Processing, Computer-AssistedMicrobiotaAlgorithmsHumansMachine Learning16S rRNADissimilarityImage-microbiomeMeta-analysisMetricSmoothingWGS

Identifiers

PMID41068935
PMCPMC12512389

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.