Evidence map›Paper›PMID 41068789›Full record

ArticleBMC pediatrics2025

Urban-rural disparity in preterm neonatal mortality in China: a retrospective study.

Yuxi Liu, Leni Kang, Yanna Zou, Xue Yu, Yiyong Su, Chongmei Huang, Juan Liang, Yanping Wang, Chunhua He, Cheng Wan

Abstract read
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Article in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Yuxi Liu *National Office for Maternal and Child Health Surveillance of China, West China Second University Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
Leni Kang *National Office for Maternal and Child Health Surveillance of China, West China Second University Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
Yanna ZouDepartment of Gynaecology and Obstetrics, Changyi Maternal and Child Care Hospital, Weifang, 261000, Shandong, China.
Xue YuNational Office for Maternal and Child Health Surveillance of China, West China Second University Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
Yiyong SuObstetrics Department, Maternity and Child Health Hospital of Yanting County, Mianyang, 621600, Sichuan, China.
Chongmei HuangObstetrics Department, China MCC5 Group Corp. Ltd. Hospital, Chengdu, 610041, Sichuan, China.
Juan LiangNational Office for Maternal and Child Health Surveillance of China, West China Second University Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
Yanping WangNational Office for Maternal and Child Health Surveillance of China, West China Second University Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
Chunhua He *National Office for Maternal and Child Health Surveillance of China, West China Second University Hospital, Sichuan University, Chengdu, 610041, Sichuan, China. hch7646@163.com.
Cheng Wan *Facilities and Maintenance Department, West China Second University Hospital, Sichuan University, Chengdu, 610041, Sichuan, China. wancheng0079@163.com.

Funding

the National Key Research and Development Program of China 2022YFC2704605
6 · The paper itself

Abstract

backgroundThe neonatal mortality rate (NMR) is a vital indicator for assessing maternal and child health, and preterm birth is one of the leading causes of neonatal mortality. Since 2010, China has implemented multiple maternal and child health policies aimed at reducing neonatal mortality. However, systematic research on urban-rural disparities in neonatal mortality among preterm births remains relatively scarce. In this study, we analyzed the national and subnational cause-specific death rates of preterm neonates in mainland China during 2010 to 2021 to provide data support for the further elimination of neonatal deaths.

methodsIn this retrospective study, we analyzed empirical data on levels and causes of preterm neonatal mortality data from the China Maternal and Child Health Surveillance System to show the cause-specific death rates, birthplaces and treatment levels at the national and subnational levels.

resultsFrom 2010 to 2021, the neonatal mortality rate due to complications of prematurity declined from 289 to 88 per 100,000 live births in rural areas, and from 126 to 41 in urban areas. Although rural rates remained higher, the absolute gap narrowed over time. According to the definitions used in the Maternal and Child Health Surveillance System (MCHSS), live births were registered only for neonates with signs of life who were born at ≥ 28 weeks of gestation or had a birth weight > 1000 g (if gestational age was unavailable), mortality was consistently highest among neonates born at 28 to 31 gestational weeks in both settings. In 2021, 95.5% of preterm neonates in urban areas were born at provincial-level hospitals, compared to 60.2% in rural areas. The proportion of preterm neonates diagnosed at county-level facilities in rural areas dropped from 46.7% to 21.8%, while in urban areas it fell from 6.5% to 2.3%.

conclusionsThis study demonstrates persistent urban-rural disparities in cause-specific mortality and gestational age distribution among preterm neonates. Findings may help local governments develop targeted strategies to further reduce overall neonatal mortality.

Indexed as

Health Status DisparitiesInfant MortalityRural PopulationUrban PopulationCause of DeathChinaFemaleHumansInfantInfant, NewbornInfant, PrematureMaleRetrospective StudiesNeonatal deathPreterm neonatesUrban–rural disparity

Identifiers

PMID41068789
PMCPMC12512810

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