ArticleWorld journal of surgical oncology2025
Young-onset versus late-onset colorectal cancer: clinicopathological features and survival outcome: a decade-long analysis from a middle Eastern tertiary center.
Article in World journal of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Hemorrhoids and Rectal Cancer: A Systematic Review of Clinical Overlap, Diagnostic Misclassification, and Early Detection Strategies for Primary Care.Journal of multidisciplinary healthcare · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundColorectal cancer (CRC) incidence is reported to be declining overall in many countries but growing among young adults. The updated American Cancer Society (ACS) guidelines recommend screening starting at age 45 years. We sought to evaluate population-level trends in young colorectal cancer (yCRC) epidemiology in Qatar, a country in the Middle East.
methodsBetween January 2010 and December 2020, we included 1529 patients from the National Registry Database with a 5-year follow-up. The patients were divided into two groups. Group 1 (n = 380, ≤ 45 years) and group 2 (n = 1149, > 45). The epidemiological and clinicopathological features were analyzed and compared in the two groups.
resultsThe annual incidence rate of CRC in Qatar from 2010 to 2020 ranged from 5.3 to 7.2 per 100,000 population, with an average of 5.79 per 100,000 population over this period. The overall prevalence among males was 65.6%. The incidence of CRC in young patients was approximately 1 in every four patients (24.8%). Males comprised almost two-thirds of the entire CRC cohort, yCRC, as well as the old-onset CRC cohort. The poorly differentiated CRC (including mucinous and signet ring features) was more prevalent in group 1 compared to group 2 (21.2% vs. 8%) (p = 0.001). Advanced CRC stages (III, IV) were significantly higher among the yCRC patients, with 63.3% of patients in group 1 diagnosed with advanced stages, compared to 59.6% (p = 0.001). Young patients with CRC were found to have more rectal involvement, with 35.6% of patients ≤ 45 years old compared to 23.9% in patients > 45 years old (p = 0.001).
conclusionThe reported incidence rate is approximately one-quarter of the newly diagnosed patients in Qatar. Patients with yCRC have a more aggressive and poorly differentiated histological type. The incidence of rectal cancer is higher in younger patients. Public awareness and screening policy have been implemented for better management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.