Evidence map›Paper›PMID 41068732›Full record

SynthesisBMC oral health2025

Accuracy of artificial intelligence in orthodontic extraction treatment planning: a systematic review and meta analysis.

SeyedMehdi Ziaei, Dorsa Samani, Mohammadreza Behjati, Ava Ostovar Ravari, Yasaman Salimi, Sina Ahmadi, Sahar Rajaei, Farnoosh Alimohammadi, Soheil Raji, Niloofar Deravi and 1 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

SeyedMehdi Ziaei *Faculty of Dentistry, Hamadan University of Medical Sciences, Hamadan, Iran.
Dorsa Samani *Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
Mohammadreza Behjati *Student Research Committee, School of Dentistry, Ardabil University of Medical Sciences, Ardabil, Iran.
Ava Ostovar RavariFaculty of Dentistry, Haybusak University of Medical Sciences, Yerevan, Armenia.
Yasaman SalimiDepartment of Periodontology, School of Dentistry, Guilan University of Medical Sciences, Rasht, Iran. yasamansalimi.1278@gmail.com.
Sina AhmadiXian jiaotong university, Xian, China.
Sahar RajaeiFaculty of dentistry, Yazd university of medical sciences, Yazd, Iran.
Farnoosh AlimohammadiDepartment of Oral Medicine, School of Dentistry, Arak University of Medical Sciences, Arak, Iran.
Soheil RajiFaculty of Dentistry, Van Yüzüncü Yıl University, Van, Türkiye, Turkey.
Niloofar DeraviStudents Research Committee, School of medicine, Shahid Beheshti University of Medical Sciences, Arabi Ave, Daneshjoo Blvd, Tehran, 19839-63113, Iran. niloofarderavi@sbmu.ac.ir.
Haleh FakhimiFaculty of dentistry, Nakhchivan State University, Nakhchivan, Azerbaijan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to evaluate the diagnostic accuracy of artificial intelligence (AI) models in predicting dental extractions during orthodontic treatment planning.

methodA systematic review and meta-analysis were conducted following PRISMA guidelines and registered in PROSPERO (CRD42024582455). Comprehensive searches were performed across PubMed, Scopus, Web Of Science, and Google Scholar up to June 2, 2025. Eligible cross-sectional studies assessing AI-based models against clinical standards were included. Data on model performance were extracted and pooled using a random-effects model. Subgroup and meta-regression analyses were conducted to explore heterogeneity.

resultsSeven cross-sectional studies from six countries with a combined sample of 6,261 patients were included. Pooled sensitivity and specificity of AI models were 70% (95% CI: 61-78) and 90% (95% CI: 87-92), respectively, though heterogeneity was high (I² = 96.7% and 93.7%). Convolutional neural networks (CNN)-based models (ResNet and VGG) demonstrated the highest diagnostic performance with no heterogeneity. Meta-regression showed that disease prevalence significantly influenced sensitivity (p = 0.050). Funnel plots revealed asymmetry, suggesting possible publication bias.

conclusionAI models, particularly CNN-based models, show promising accuracy in predicting the need for orthodontic extractions. Therefore, they can be used to create predictive models for orthodontic extractions to increase accuracy. Due to the high heterogeneity, further large-scale studies are needed to support clinical implementation.

Indexed as

Artificial IntelligencePatient Care PlanningTooth ExtractionCross-Sectional StudiesHumansNeural Networks, ComputerSensitivity and SpecificityArtificial intelligenceMeta-AnalysisOrthodonticsOrthodontic tooth extractionSystematic reviewTechnologyTreatment planning

Identifiers

PMID41068732
PMCPMC12512631

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.