Trial reportBMC oral health2025
Evaluation of the effects of calcium hydroxide-based, calcium silicate-based, and epoxy resin-based sealers on postoperative pain after a single session non-surgical endodontic retreatment: a randomized clinical trial.
Trial report in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06803277 (Evaluation of Post Operative Pain After a Single Session of Endodontic Retreatment Using Different Root Canal Sealers), which is not on this map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of Post Operative Pain After a Single Session of Endodontic Retreatment Using Different Root Canal Sealers
Who cites it
2 citing papers in PubMed.
- Comparative efficacy of two novel bioceramic root canal sealers in the treatment of chronic apical periodontitis.Medicine · 2026Article
- The effects of zinc oxide eugenol, calcium hydroxide, bioactive glass, resin and bioceramic canal sealers on post-operative pain: A randomized clinical trial.Bioinformation · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
objectivesThis randomized clinical trial aimed to evaluate the effect of calcium hydroxide-based, calcium silicate-based and epoxy resin-based root canal sealers on postoperative pain (PP) after a single session of non-surgical endodontic retreatment of the teeth with chronic apical periodontitis. MATERIALS AND
methodsNinety-six participants who had teeth with previously root canal treatment, asymptomatic, a single root and single canal, chronic apical periodontitis, were included in the study and then were randomly allocated to one of three experimental groups. (n = 32 per group).An endodontic specialist performed same retreatment protocols in a single visit. Participants were asked to rate the intensity of PP on a visual analogue scale at 6, 12, 24, and 48 h, and 3, 4,5, 6, and 7 days, and to mark whether they had taken analgesic (400 mg Ibuprofen) during the same periods after retreatment. All statistical analyses were performed using a software program (IBM SPSS Statistics, Version 22), and the significance level was set at P < 0.05.
resultsThere was no significant difference between the groups in PP and analgesic intake at any of the time intervals evaluated(P > 0.05).A strong positive correlation was observed at 48 h and 96 h when the correlation between PP and analgesic intake was evaluated regardless of the type of root canal sealer. PP level was associated with age, gender, Periapical Index (PAI) score, and jaw type.(P < 0 0.05).
conclusionsEpoxy resin, Calcium silicate, and calcium hydroxide-based root canal sealers resulted in statistically similar postoperative pain levels. CLINICAL SIGNIFICANCE: Each of the epoxy resin, calcium silicate, and calcium hydroxide-based root canal filling materials could be used safely in patients when considering PP.
trial registrationClinicalTrial.gov, NCT06803277, record date: 2025-01-17, retrospectively registered.
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Registered trials
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