Evidence map›Paper›PMID 41068711›Full record

SynthesisBMC oral health2025

Systematic review and standardized comparison of health-related quality-of-life instruments available for patients with oral cavity cancer and oropharyngeal cancer.

Naira Figueiredo Deana, Carolina Ulloa, Francisco Ceballos, Nilton Alves, Rodrigo Mariño, Wilfredo Alejandro González-Arriagada, Carlos Zaror

Abstract readSystematic ReviewComparative Study
In one paragraph

Synthesis in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Naira Figueiredo DeanaCenter for Research in Epidemiology, Economics and Oral Public Health (CIEESPO), Faculty of Dentistry, Universidad de La Frontera, Temuco, Chile.
Carolina UlloaBucomaxillofacial Surgery and Traumatology Group, Complejo Asistencial Padre Las Casas, Padre Las Casas, Chile.
Francisco CeballosFaculty of Dentistry, Master Program in Dentistry, Universidad de La Frontera, Temuco, Chile.
Nilton AlvesApplied Morphology Research Centre (CIMA), Faculty of Dentistry, Universidad de La Frontera, Temuco, Chile.
Rodrigo MariñoCenter for Research in Epidemiology, Economics and Oral Public Health (CIEESPO), Faculty of Dentistry, Universidad de La Frontera, Temuco, Chile.
Wilfredo Alejandro González-ArriagadaFaculty of Dentistry, Universidad de Los Andes, Santiago, Chile.
Carlos ZarorCenter for Research in Epidemiology, Economics and Oral Public Health (CIEESPO), Faculty of Dentistry, Universidad de La Frontera, Temuco, Chile. carlos.zaror@ufrontera.cl.

Funding

Universidad de La Frontera DI20-0054Universidad de La Frontera PUA23-0006
6 · The paper itself

Abstract

backgroundTo identify HRQoL instruments available for oral cavity cancer (OCC) or oropharyngeal cancer (OC) patients and to summarize the evidence on conceptual model measurement, psychometric and administration properties. MATERIALS AND

methodsWe searched MEDLINE, CENTRAL, EMBASE, and LILACS until April 2023. We included studies evaluating the concept model measurement, psychometric and administration properties of instruments measuring HRQoL in OCC or OC patients. Two researchers assessed each instrument independently, using the Evaluating Measures of Patient-Reported Outcomes (EMPRO) tool. We calculated the overall and seven attribute-specific scores (range 0-100) using the conceptual and measurement model, reliability, validity, responsiveness, interpretability, burden, and alternative forms.

resultsWe included seven instruments across 42 articles. The overall EMPRO score of these instruments varied between 84.1 and 29.3, with five questionnaires exceeding the threshold score of 50.0. The domains of conceptual and measurement model and interpretability performed best, while responsiveness exhibited the lowest performance.

conclusionsThe findings support the use of EORTC QLQ-H&N43, EORTC QLQ-C30, and EORTC QLQ-OH15 as suitable HRQoL instruments for both cross-sectional or longitudinal studies to measure physical, symptomatic, psychological, or social impacts in patients with OCC or OC. FACT-H&N and UW-QoL were deemed appropriate for evaluating HRQoL in cross-sectional studies in these patients.

Indexed as

Mouth NeoplasmsOropharyngeal NeoplasmsQuality of LifeHumansPatient Reported Outcome MeasuresPsychometricsReproducibility of ResultsSurveys and QuestionnairesEMPRO toolHead and Neck cancerHealth-related quality of lifeMouth neoplasmsOropharyngeal neoplasmsPsychometric properties

Identifiers

PMID41068711
PMCPMC12512785

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.