Evidence map›Paper›PMID 41068703›Full record

Trial reportBMC psychiatry2025

Motivation in the Bergen 4-day treatment for obsessive-compulsive disorder.

Håvard Berg, Kristian Tjelle, Stian Solem, Bjarne Hansen, Gerd Kvale, Thröstur Björgvinsson, Kristen Hagen

Registry-linked trialAbstract readClinical Trial, Phase IVMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02656342 (Translational Approach to the Understanding and Treatment of Obsessive-Compulsive Disorder), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02656342 phase4completednot on this map

Translational Approach to the Understanding and Treatment of Obsessive-Compulsive Disorder (OCD). Can D-Cycloserine Enhance and Stabilize the Treatment-response in Relapsed and Non-responding OCD-patients? A Randomized, Double-blind, Placebo-controlled National Study

TypeinterventionalSponsorHaukeland University HospitalRan2015 to 2019Enrolled163ConditionsObsessive-Compulsive DisorderArmsD-Cycloserine, Placebo
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Håvard BergDepartment of Psychiatry, Møre og Romsdal Hospital Trust, Molde Hospital, Molde, 6412, Norway.
Kristian TjelleDepartment of Psychiatry, Møre og Romsdal Hospital Trust, Molde Hospital, Molde, 6412, Norway.
Stian SolemDepartment of Psychology, Norwegian University of Science and Technology, Trondheim, Norway.
Bjarne HansenBergen Center for Brain Plasticity, Haukeland University Hospital, Bergen, Norway.
Gerd KvaleBergen Center for Brain Plasticity, Haukeland University Hospital, Bergen, Norway.
Thröstur BjörgvinssonBehavioral Health Partial Hospital Program, Harvard Medical School, McLean Hospital, Belmont, MA, USA.
Kristen HagenDepartment of Psychiatry, Møre og Romsdal Hospital Trust, Molde Hospital, Molde, 6412, Norway. kristen.hagen@helse-mr.no.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study investigated the associations among treatment motivation, patient adherence, and treatment outcomes in a group of outpatients with difficult-to-treat obsessive–compulsive disorder (OCD).

methodsA total of 163 relapsed or nonresponding patients were treated with the Bergen 4-day treatment. Motivation was measured with a modified version of the Nijmegen Motivational List 2 (NML2) prior to the start of treatment. During treatment, patients rated their own adherence using the Patient Exposure and Response Prevention (EX/RP) Adherence Scale (PEAS). Treatment outcomes were assessed with the Yale-Brown Obsessive Compulsive Scale (Y-BOCS) at posttreatment and 3-month follow-up.

resultsThe NML2 items related to commitment showed a weak but significant association with treatment outcomes but were not significant when patient adherence was controlled for. Higher adherence was strongly associated with better treatment outcomes. DISCUSSION: Self-reported motivation before the start of treatment had limited predictive validity, whereas in- and between-session patient adherence, which could reflect one aspect of the motivation construct (treatment engagement), was important for recovery.

trial registrationClinicalTrials.gov identifier: NCT02656342 (First registered: 2015–11–30).

Indexed as

Cognitive Behavioral TherapyMotivationObsessive-Compulsive DisorderPatient ComplianceAdultFemaleHumansMaleMiddle AgedTreatment OutcomeCBTCommitmentComplianceERPOCDRCTTreatment engagement

Identifiers

PMID41068703
PMCPMC12512304

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.