Evidence map›Paper›PMID 41068684›Full record

ArticleBMC ophthalmology2025

Long-term observation of glare and dynamic pupil after EVO ICL (implantable collamer lens) for myopia.

Xun Chen, Wuxiao Zhao, Jifang Wang, Mingrui Cheng, Xiaoying Wang, Xingtao Zhou

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Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Xun Chen *Fudan University Eye Ear Nose and Throat Hospital, Shanghai, 200031, China.
Wuxiao Zhao *Fudan University Eye Ear Nose and Throat Hospital, Shanghai, 200031, China.
Jifang Wang *Fudan University Eye Ear Nose and Throat Hospital, Shanghai, 200031, China.
Mingrui ChengFudan University Eye Ear Nose and Throat Hospital, Shanghai, 200031, China.
Xiaoying WangFudan University Eye Ear Nose and Throat Hospital, Shanghai, 200031, China. doctxiaoyingwang@163.com.
Xingtao ZhouFudan University Eye Ear Nose and Throat Hospital, Shanghai, 200031, China. doctzhouxingtao@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the long-term changes in glare and dynamic pupil after EVO ICL implantation in myopic patients and their influencing factors.

methodIn this prospective, consecutive case study, 22 patients (44 eyes, Male/Female = 9/13) underwent EVO-ICL, with a mean age of 25.3 ± 5.4 years and spherical equivalent of -10.52 ± 3.02 D (range: -3.25 D ~ -18.00 D). Comprehensive examinations were performed before and after surgery and all patients were followed up for 5 years.

resultAt the final follow-up, the efficacy and safety indexes were 0.95 ± 0.28 and 1.17 ± 0.19, respectively. The postoperative glare decreased significantly at 1 week and 1 month (P < 0.01), then stabilized (P > 0.05). 16/22 (72.7%) of the patients reported glare. Of these patients, 7/22 (31.8%) experienced glare bothersomeness, all rating mild. Additionally, 4/22 (18.2%) of the patients had mild problems with night-time driving. In dynamic pupillometry, the amplitude of pupil contraction significantly decreased during early period (P = 0.001), and restored after 5 years post-surgery (P = 0.081). Moreover, the pupil contraction and dilation velocity reduced significantly in the early-stage (P < 0.01), and later recovered after 5 years of surgery (P > 0.05). The maximum pupil diameter did not alter significantly in the early-stage, however, it significantly decreased after 5 years post-surgery (P = 0.001). GEE showed that pupil dilation velocity, maximum pupil diameter, and ICL size were positively correlated with postoperative glare and were the main influences on the latter (all P < 0.01).

conclusionEVO ICL is safe and effective in correcting myopia. Post-operative glare is related to the pupil dilation velocity, maximum pupil diameter, and decreases over time. Most patients have no glare bothersomeness in the long term, some patients may even have their glare symptoms disappear. Only a few patients experience slight interference while nighttime driving.

Indexed as

GlareLens Implantation, IntraocularMyopiaPhakic Intraocular LensesPupilAdultFemaleFollow-Up StudiesHumansMaleProspective StudiesRefraction, OcularTime FactorsVisual AcuityYoung AdultEVO-ICLGlareMyopiaPupillometry

Identifiers

PMID41068684
PMCPMC12512749

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.