Evidence map›Paper›PMID 41068640›Full record

ArticleBMC pediatrics2025

Altered right inferior frontal gyrus-based functional connectivity associated with inhibition through swimming exercise in children with attention deficit hyperactivity disorder.

Li Ding, Wei Zhong, Lihan Chen, Huijuan Shen, Lin Chen, Kaihua Jiang

Abstract read
In one paragraph

Article in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Li Ding *Department of Pediatrics, Changzhou Children's Hospital of Nantong University, Changzhou, China.
Wei Zhong *School of Humanities, Shanghai Normal University, Shanghai, China.
Lihan ChenBusiness School, XI'AN International Studies University, Xi'an, China.
Huijuan ShenDepartment of Pediatrics, Changzhou Children's Hospital of Nantong University, Changzhou, China.
Lin Chen *Department of Psychiatry, Changzhou De'an Hospital, Changzhou, China. wawalin5@126.com.
Kaihua Jiang *Department of Pediatrics, Changzhou Children's Hospital of Nantong University, Changzhou, China. jkh23z59@163.com.

Funding

the scientific research project of Changzhou Medical Center of Nanjing Medical University CMCC202316the scientific research project of Jiangsu Provincial Health Commission M2024028top-notch talent of the Health Commission of Changzhou 2022CZBJ092
6 · The paper itself

Abstract

backgroundAttention deficit hyperactivity disorder (ADHD) is a common clinical developmental disorder. Aerobic exercise effectively improves the inhibition function of ADHD children, but its intervention mechanism is not clear yet. This study aimed to explore the brain mechanisms of aerobic exercise improving inhibitory function in children with ADHD.

methods20 school-age children with ADHD were studied. Before and after swimming exercise three times a week for 8 weeks, resting-state functional magnetic resonance imaging (rs-fMRI) and Flanker task tests were performed respectively. fMRI analysis focused on the right inferior frontal gyrus (rIFG), and the whole-brain functional connectivity (FC) was calculated based on rIFG. Paired t-test was used to analyze the FC value and the behavioral results of the Flanker task. And the correlations between the FC and the behavioral changes before and after swimming exercise were analyzed.

resultsThis study found that the brain regions with significant differences in rIFG-based FC values included rIFG, right inferior parietal lobule, and cerebellum posterior lobe. The response time after exercise was significantly shorter than that before exercise, while the accuracy after exercise was higher than before. And, the FC changes within rIFG were negatively correlated with the response time changes and positively correlated with the accuracy changes of the Flanker task.

conclusionThis study suggests that the FC within rIFG and the FC between rIFG and right inferior parietal lobule are related to the improvement of inhibition function in ADHD children.

Indexed as

Attention Deficit Disorder with HyperactivityExerciseExercise TherapyInhibition, PsychologicalPrefrontal CortexSwimmingChildFemaleHumansMagnetic Resonance ImagingMaleAerobic exerciseAttention deficit hyperactivity disorderFunctional connectivityFunctional magnetic resonance imagingInhibition

Identifiers

PMID41068640
PMCPMC12512462

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.