Evidence map›Paper›PMID 41068621›Full record

ArticleBMC ophthalmology2025

Incidence and risk factors for early transient intraocular pressure elevation after penetrating canaloplasty in patients with glaucoma.

Lijuan Xu, Juan Gu, Wenqing Ye, Xinyao Zhang, Yin Zhao, Tao Zhou, Jialing Han, Ruiyi Ren, Yuanbo Liang

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In one paragraph

Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Lijuan XuNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.
Juan GuNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.
Wenqing YeNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.
Xinyao ZhangNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.
Yin ZhaoNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.
Tao ZhouNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.
Jialing HanNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.
Ruiyi RenNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.
Yuanbo LiangNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China. yuanboliang@wmu.edu.cn.

Funding

Health Commission of Zhejiang Province 2023KY914Research Jump-start Funds from the Eye Hospital of Wenzhou Medical University KYQD20240107the Excellent Young Ophthalmologist Training Program of the Eye Hospital of Wenzhou Medical University ZYQNYS202405the Key Project of Basic Research Funds of Wenzhou Medical University KYYW202301the Key R&D Program of Zhejiang 2022C03112the National Nature Science Foundation of China 82201177the National Nature Science Foundation of China 82471076
6 · The paper itself

Abstract

backgroundThis study aimed to evaluate the incidence and risk factors for early transient intraocular pressure (IOP) elevation after penetrating canaloplasty (PCP) in patients with primary open-angle glaucoma (POAG), primary angle-closure glaucoma (PACG) and secondary glaucoma (SG).

methodsThis retrospective study included 198 eyes of 198 patients with glaucoma. Participants were classified as normal IOP, early transient high IOP (E-HIOP [Tst]), early persistent IOP elevation, late transient high IOP, and late persistent IOP elevation, based on the period and persistence of postoperative IOP elevation.

resultsE-HIOP (Tst) developed in 34.8%, 33.3%, and 40.9% of eyes with POAG, PACG, and SG, respectively. In comparison with normal IOP group, we observed the following variations in E-HIOP (Tst) cohorts: 8 - 10 years younger in patients with POAG and PACG; higher prevalence of hyphema (45.5% vs. 20.5%) in POAG; higher baseline IOP in PACG and SG (7 - 8 mmHg); higher preoperative IOP maximum (IOP

conclusionsNearly 30 - 40% of eyes developed E-HIOP (Tst) after PCP. E-HIOP (Tst) tended to develop in younger participants and those with higher preoperative IOP. A higher IOP

Indexed as

GlaucomaIntraocular PressureOcular HypertensionPostoperative ComplicationsAdultFemaleFiltering SurgeryFollow-Up StudiesGlaucoma, Angle-ClosureGlaucoma, Open-AngleHumansMaleMiddle AgedMinimally Invasive Surgical ProceduresRisk FactorsTonometry, OcularEarly postoperative IOP elevationGlaucomaPenetrating canaloplastyRisk factor

Identifiers

PMID41068621
PMCPMC12512409

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.