ReviewNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2026
Striatal and hippocampal contributions to value-based learning in adolescence.
Review in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Impulsivity in adolescents with MDD and non-suicidal self-injury: a multimodal assessment using psychometric, behavioral, and neurophysiological measures.Child and adolescent psychiatry and mental health · 2026Article
- Premature release of action sequences in adolescent male rats.Frontiers in behavioral neuroscience · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Adaptive value-based learning is a complex challenge supported by neurobiological systems based in the striatum and hippocampus, with important implications for both everyday behaviors and for mental health. In adults, these systems have been shown to compete, complement, and integrate; less is known about this interplay earlier in development. Here, we discuss representative empirical evidence for the roles of striatum-PFC and hippocampus-PFC systems and their interactions in developing goal-directed behaviors during adolescence. These systems are also implicated in value-based learning alterations in adolescent-emergent mental health disorders. More focus on interactions between value-based learning systems in adolescence, a time of sensitivity to reward and opportunity for mental health interventions, is necessary to support development across healthy and clinical populations. We propose that differential timing of striatum-PFC and hippocampus-PFC network maturation may shape distinct adolescent behavioral phenotypes.
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Registered trials
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