Evidence map›Paper›PMID 41068333›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2026

Quantification of illicit and prescription drug residues in pasteurized donor human milk: a comprehensive analytical approach.

Michelle Brenner, Kaytlin Krutsch, Ashlynn Baker, Dhavalkumar Patel, Palika Datta

Abstract read
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Drug exposures in donor milk: protecting our most vulnerable infants.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Michelle Brenner *The King's Daughters Milk Bank, Children's Hospital of The Kings Daughters, Department of Pediatrics, Macon & Joan Brock Virginia Health Sciences at Old Dominion University, Norfolk, VA, USA. michelle.brenner@chkd.org.ORCID http://orcid.org/0009-0003-9687-4799
Kaytlin Krutsch *Texas Tech University Health Sciences Center InfantRisk Center, Amarillo, TX, USA.
Ashlynn BakerThe King's Daughters Milk Bank, Children's Hospital of The Kings Daughters, Department of Pediatrics, Macon & Joan Brock Virginia Health Sciences at Old Dominion University, Norfolk, VA, USA.
Dhavalkumar PatelDepartment of Pharmaceutical Sciences, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, TX, USA.ORCID http://orcid.org/0000-0002-6959-3487
Palika DattaTexas Tech University Health Sciences Center InfantRisk Center, Amarillo, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the risk of infant exposure to illicit and prescription drug residues, from infant-ready, pooled, pasteurized donor human milk (PDHM) provided by healthy, screened, voluntary non-remunerated donors to a not-for-profit milk bank. STUDY

designA total of 150 pooled samples, representing 742 donor contributions, were analyzed for 15 illicit and prescription drug analytes using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Detected concentrations were evaluated for clinical significance.

resultAll 150 PDHM samples tested negative for residues of marijuana, amphetamines, benzodiazepines, fentanyl, hydrocodone, and morphine. Three samples (2%) contained trace amounts of oxycodone (<0.6 parts per billion), yielding exposures over 455 times lower than established standards for infant safety (Relative Infant Dose: <0.022%; standard safety threshold 10%).

conclusionComprehensive analysis detected no clinically relevant illicit or prescription drug residues in infant-ready pasteurized donor human milk, supporting both its safety for neonatal consumption and the effectiveness of current donor screening protocols and milk processing practices.

Indexed as

Drug ResiduesIllicit DrugsMilk, HumanPrescription DrugsChromatography, LiquidFemaleHumansInfantInfant, NewbornMilk BanksPasteurizationTandem Mass SpectrometryIllicit DrugsPrescription Drugs

Identifiers

PMID41068333
PMCPMC13120995

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.