Evidence map›Paper›PMID 41068307›Full record

SynthesisArchives of women's mental health2025

Association between suicidal behaviour in pregnant women and pregnancy and fetal outcomes: A systematic review and meta-analysis.

Maitry Sukhadeve, Farhan Farooque Khan, Nishaant Ramasamy, Akanksha P Dani, Swapnajeet Sahoo, Prachi Dixit, Aravind P Gandhi

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Archives of women's mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maitry Sukhadeve *MBBS, All India Institute of Medical Sciences (AIIMS), Nagpur, India.
Farhan Farooque Khan *Department of Public Health, Taluka Health Officer, Government of Maharashtra, Nashik, Maharashtra, India.
Nishaant Ramasamy *Senior Resident, Department of Community Medicine, All India Institute of Medical Sciences (AIIMS), Nagpur, India.
Akanksha P DaniSenior Resident, Department of Community Medicine, All India Institute of Medical Sciences(AIIMS), Nagpur, India.ORCID 0000-0002-2840-2699
Swapnajeet SahooAssociate Professor, Department of Psychiatry, PGIMER, Chandigarh, India.ORCID 0000-0003-0365-7086
Prachi DixitAssistant Professor, Department of Obstetrics and Gynecology, All India Institute of Medical Sciences (AIIMS), Nagpur, India.
Aravind P GandhiAssistant Professor, Department of Community Medicine, All India Institute of Medical Sciences(AIIMS), Nagpur, India. aravindsocialdoc@gmail.com.ORCID 0000-0003-3898-5450

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSuicidal behavior during pregnancy, including ideation, planning, and attempts, represents a significant but under-researched public health concern linked to adverse maternal and fetal outcomes such as preterm labor, low birth weight, and stillbirth. This systematic review and meta-analysis (SRMA) aimed to synthesize evidence on the association between suicidal behavior during pregnancy and feto-maternal outcomes, addressing existing gaps in the literature. MATERIALS AND

methodsThe SRMA, following PRISMA 2020 guidelines, included observational studies that reported maternal and fetal outcomes among pregnant women exhibiting suicidal behaviour (suicidal ideation, planning, or attempts). Four databases (PubMed, Embase, Web of Science, and Cochrane) were searched up to April 30, 2025, and 18 studies were included. Risk of bias assessment was done using the Newcastle-Ottawa scale. Data were analysed using random-effects models to calculate pooled relative risks (RRs) and 95% confidence intervals (CIs).

resultsFrom the 18 studies included for the SRMA, a total of 30749705 participants were analysed, with 6557 in the suicidal behaviour group. Suicidal behaviour significantly increased the risk of preterm labor (RR = 1.78, 95% CI: 1.7-1.86), preterm birth (RR = 1.40, 95% CI: 1.26-1.55), fetal anomaly (RR = 1.84, 95% CI: 1.22-2.77) and Low Birth Weight (RR = 1.83, 95% CI: 1.67-2.02), with no heterogeneity observed (I² = 0%). Stillbirth risk was markedly elevated (RR = 11.92, 95% CI: 10.32-13.77). Other outcomes, such as placental abruption and postpartum hemorrhage, also demonstrated increased risks. All the outcomes had a low to very low certainty of evidence.

conclusionSuicidal behaviour during pregnancy poses significant risks to maternal and fetal health, emphasizing the need for early identification and interventions. Addressing maternal mental health must be prioritized in prenatal care to improve outcomes for both mother and child. Others: The protocol was registered in the PROSPERO (ID: CRD42024539860).

Indexed as

Pregnancy ComplicationsPregnancy OutcomePregnant PeopleSuicidal IdeationSuicide, AttemptedFemaleHumansInfant, NewbornPregnancyPremature BirthRisk FactorsStillbirthFeto-maternal outcomesGRADE assessment.Low birth weightPregnancyPreterm labourSuicidal behaviour

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.