Evidence map›Paper›PMID 41068281›Full record

ArticleScientific reports2025

Advanced transformer with attention-based neural network framework for precise renal cell carcinoma detection using histological kidney images.

M Eliazer, Guntupalli Manoj Kumar, Sibi Amaran, Y Shasikala, Monalisa Sahu, Bibhuti Bhusan Dash, Kanchan Bala

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Predicting ki-67 expression in breast cancer via transformer and multiple instance learning on DCE-MRI.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

M EliazerDepartment of Computing Technologies, SRM Institute of Science and Technology, Kattankulathur, 603203, India.
Guntupalli Manoj KumarDepartment of Computing Technologies, SRM Institute of Science and Technology, Kattankulathur, 603203, India.
Sibi AmaranDepartment of Computing Technologies, SRM Institute of Science and Technology, Kattankulathur, 603203, India.
Y ShasikalaDepartment of Computer Applications, Aditya University, Surampalem, Andhra Pradesh, 533437, India.
Monalisa SahuSchool of Computer Science & Engineering, VIT AP University, Amaravati, Andhra Pradesh, India. monalisa.sahu@vitap.ac.in.
Bibhuti Bhusan DashSchool of Computer Applications, KIIT Deemed to be University, Bhubaneswar, India.
Kanchan BalaDepartment of Computer Science and Engineering, Gaya College of Engineering, Gaya, Bihar, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal cell carcinoma (RCC) is one of the typical categories of kidney cancer and is a varied group of malignancies arising from epithelial cells of the kidney parenchyma. RCC has more than ten subtypes. Classification of RCC sub-types is mainly according to morphologic features seen on histopathological hematoxylin and eosin (H & E)-stained slides. The histology classification of RCCs is of great significance, considering the important therapeutic and prognostic implications of its histologic subtypes. Imaging models play a prominent role in the diagnosis, follow-up, and staging of RCC. Histopathological images comprise morphological markers of disease development that have both predictive and diagnostic value. Recently, deep learning (DL) has achieved advanced performance in various computer vision tasks, including segmentation, image classification, and object detection. With the provision of sufficient data, the precision of a DL-enabled diagnosis model frequently matches or even exceeds that of qualified doctors. This paper presents an Advanced Transformer and Attention-Based Neural Network Framework for the Intelligent Detection of Renal Cell Carcinoma (ATANNF-IDRCC) model. The aim is to develop an accurate and automated model for detecting and ranking RCC using kidney histopathology images. Initially, the image pre-processing stage utilizes the contrast enhancement method to enhance the image quality. Furthermore, the ATANNF-IDRCC model utilizes the Twins-Spatially Separable Vision Transformer (Twins-SVT) method for feature extraction. For the RCC classification process, a hybrid model of bidirectional temporal convolutional network and long short-term memory with an attention mechanism (BiTCN-BiLSTM-AM) is employed. The performance analysis of the ATANNF-IDRCC technique is examined under the RCCGNet dataset. The comparison study of the ATANNF-IDRCC technique demonstrated a superior accuracy value of 98.26% compared to existing models.

Indexed as

Carcinoma, Renal CellImage Processing, Computer-AssistedKidneyKidney NeoplasmsNeural Networks, ComputerAlgorithmsDeep LearningHumansImage Interpretation, Computer-AssistedAttention-based neural networkBiomedical image analysisComputer visionHistopathology imagesHybrid deep learningRenal cell carcinoma

Identifiers

PMID41068281
PMCPMC12511621

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