Evidence map›Paper›PMID 41068213›Full record

ArticleScientific reports2025

Association between toothbrushing habits and hypertension in the general population.

Ayano Tezuka, Takuro Kubozono, Takeko Kawabata, Shin Kawasoe, Satoko Ojima, Satoshi Yamaguchi, Yuichi Akasaki, Koji Higuchi, So Kuwahata, Toshihiro Takenaka and 4 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ayano TezukaDepartment of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan.
Takuro KubozonoDepartment of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan. kubozono@m.kufm.kagoshima-u.ac.jp.
Takeko KawabataDepartment of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan.
Shin KawasoeDepartment of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan.
Satoko OjimaDepartment of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan.
Satoshi YamaguchiDepartment of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan.
Yuichi AkasakiDepartment of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan.
Koji HiguchiDepartment of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan.
So KuwahataDepartment of Internal and Cardiovascular Medicine, Tarumizu Chuo Hospital, Tarumizu Municipal Medical Center, Kagoshima, Japan.
Toshihiro TakenakaDepartment of Internal and Cardiovascular Medicine, Tarumizu Chuo Hospital, Tarumizu Municipal Medical Center, Kagoshima, Japan.
Keitaro NishiDepartment of Maxillofacial Diagnostic and Surgical Science, Field of Oral and Maxillofacial Rehabilitation, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
Maya NakamuraDepartment of Maxillofacial Diagnostic and Surgical Science, Field of Oral and Maxillofacial Rehabilitation, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
Tatsuo OkuiDepartment of Maxillofacial Diagnostic and Surgical Science, Field of Oral and Maxillofacial Rehabilitation, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
Mitsuru OhishiDepartment of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontitis has been linked to cardiovascular disease (CVD), suggesting that oral care may play a role in CVD prevention. In contrast, hypertension has been linked to oral health; however, its association with toothbrushing habits is unclear. Therefore, this study aimed to investigate the relationship between toothbrushing habits and hypertension. A total of 941 participants (361 men, mean age: 67 ± 11 years) from a 2019 community-based study conducted in Tarumizu City were included. Hypertension was defined as systolic BP ≥ 140 mmHg, diastolic BP ≥ 90 mmHg, or use of antihypertensive medications. Toothbrushing habits were assessed using a questionnaire, and oral health was evaluated by dentists. The mean BP was 132 ± 17/78 ± 11 mmHg, with a hypertension prevalence of 56%. Participants reported toothbrushing rates of 33% upon waking, 8% before breakfast, 69% after breakfast, 48% after lunch, 4% before dinner, 42% after dinner, and 51% before sleeping. In the univariable analysis, both the timing of toothbrushing (after breakfast, after lunch, or before sleeping) and brushing frequency (≥ 3 times/day) were significantly associated with a lower prevalence of hypertension. Multivariable analysis revealed a significant association between toothbrushing after breakfast and hypertension. In conclusion, toothbrushing after breakfast was independently associated with a reduced risk of hypertension.

Indexed as

HypertensionToothbrushingAgedFemaleHumansJapanMaleMiddle AgedOral HealthPrevalenceRisk FactorsSurveys and QuestionnairesBlood pressureHypertensionOral statusToothbrushing habits

Identifiers

PMID41068213
PMCPMC12511358

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.