Evidence map›Paper›PMID 41067261›Full record

ArticleJournal of reconstructive microsurgery2026

Impact of Obesity on Surgical and Patient-Reported Outcomes Following Immediate Lymphatic Reconstruction.

Abbas M Hassan, John P Hajj, John P Lewis, Carla S Fisher, Folasade O Imeokparia, Kandice K Ludwig, Rachel M Danforth, R Jason VonDerHaar, Ravinder Bamba, Mary E Lester and 1 more

Abstract read
In one paragraph

Article in Journal of reconstructive microsurgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Abbas M HassanDivision of Plastic Surgery, Indiana University School of Medicine, Indianapolis, Indiana, United States.
John P HajjDivision of Plastic Surgery, Indiana University School of Medicine, Indianapolis, Indiana, United States.
John P LewisDivision of Plastic Surgery, Indiana University School of Medicine, Indianapolis, Indiana, United States.
Carla S FisherDivision of Breast Surgery, Indiana University School of Medicine, Indianapolis, Indiana, United States.
Folasade O ImeokpariaDivision of Breast Surgery, Indiana University School of Medicine, Indianapolis, Indiana, United States.
Kandice K LudwigDivision of Breast Surgery, Indiana University School of Medicine, Indianapolis, Indiana, United States.
Rachel M DanforthDivision of Plastic Surgery, Indiana University School of Medicine, Indianapolis, Indiana, United States.
R Jason VonDerHaarDivision of Plastic Surgery, Indiana University School of Medicine, Indianapolis, Indiana, United States.
Ravinder BambaDivision of Plastic Surgery, Indiana University School of Medicine, Indianapolis, Indiana, United States.
Mary E LesterDivision of Plastic Surgery, Indiana University School of Medicine, Indianapolis, Indiana, United States.
Aladdin H HassaneinDivision of Plastic Surgery, Indiana University School of Medicine, Indianapolis, Indiana, United States.

Funding

Novel Mechanisms in the Resolution of Post-Surgical LymphedemaK08HL167164 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI Aladdin Hasan Hassanein · 2023 to 2026
$595k
National Institute of Health Sciences K08HL167164NHLBI NIH HHS K08 HL167164
6 · The paper itself

Abstract

Background: While obesity is a known risk factor for developing breast cancer-related lymphedema (BCRL) after axillary lymph node dissection (ALND), its impact on outcomes of immediate lymphatic reconstruction (ILR) is yet to be elucidated. The purpose of this study is to assess the influence of obesity on BCRL incidence and patient-reported outcomes following ILR. Methods: We retrospectively studied consecutive patients who underwent ILR following ALND between 2017 and 2024 across a university hospital system. BCRL prevalence and condition-specific (LYMPH-Q) quality-of-life performance were compared and correlated via multivariable regression. Results: We identified 172 patients (mean body mass index [BMI]: 29.5 ± 6.9 kg/m Conclusion: ILR mitigated the risk of BCRL associated with obesity following ALND. However, obesity remained associated with significantly worse patient-reported lymphedema symptom burden following ILR. These findings highlight a dissociation between objective risk reduction and subjective symptom burden, underscoring the need for integrated assessment and targeted symptom management protocols.

Indexed as

Breast NeoplasmsLymphedemaLymph Node ExcisionObesityPlastic Surgery ProceduresPostoperative ComplicationsAdultAgedAxillaBody Mass IndexFemaleHumansIncidenceMiddle AgedPatient Reported Outcome MeasuresQuality of Life

Identifiers

PMID41067261
PMCPMC13022778

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.