SynthesisJournal of geriatric oncology2025
Treatment decision-making and quality of life versus length of life preferences of older patients with early stage cancer: A systematic review.
Synthesis in Journal of geriatric oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- [Geriatric assessments and their practical application in uro-oncology : How do we decide on prostate cancer treatment in an age-appropriate way?]Urologie (Heidelberg, Germany) · 2026Guideline
- Esophagectomy in Octogenarians in the Minimally Invasive Era: A NSQIP Analysis of Surgical Outcomes.Journal of clinical medicine · 2026Article
- EBCC-15 manifesto: Removing age-related barriers to improve equity in breast cancer care.Breast (Edinburgh, Scotland) · 2026Review
- Neoplastic Disorders and Cardiovascular Comorbidities in Geriatric Patients: A Simple Association?Geriatrics (Basel, Switzerland) · 2026Review
- General healthcare preferences for people aged 50 and over in England: English longitudinal study of ageing.PloS one · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionTo fully consider the preferences and information needs of older adults, cancer treatment decision-making discussions should take a patient-centred approach. Some older patients may place more value on maintaining quality of life over the continuation of life-prolonging treatments, even when the cancer is early-stage and potentially curable. Decision support tools can play a role in facilitating discussions around treatment trade-offs. The objective of this review is to examine the literature on the treatment decision-making preferences of patients aged 70 and older with early-stage, potentially curable, cancer. MATERIALS AND
methodsMEDLINE OVID, CINAHAL, APA PsycINFO, Scopus, and Cochrane databases were systematically searched in January 2025. Published literature focusing on quality and length-of-life decision-making, and the use of decision support tools aimed towards older adults diagnosed with early-stage cancer, were included. Two authors performed full-text selection and quality appraisal. Data were synthesized according to themes, using the Framework Approach.
resultsFrom 1476 screened records, a total of 14 studies were included. Five key themes were identified: Information needs; Treatment preferences; Trade-offs (treatments, quality and length-of-life); Decision-making involvement; Available decision support interventions. DISCUSSION: Evidence suggests that older patients would benefit from receiving information about both quality and length-of-life when making cancer treatment decisions. Quality of life concerns including physical wellbeing, autonomy, and symptom burden were factors considered by patients. Decision support tools have the potential to assist in trade-off discussions, however, few have been developed to balance trade-offs between quality and length-of-life. REGISTRATION: PROSPERO: CRD42025626454.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.