Evidence map›Paper›PMID 41066792›Full record

ArticleEmerging microbes & infections2025

Influenza NS1 drives N

Yingyin Liao, Jiayan Liu, Pui Wang, Bobo Wing-Yee Mok, Honglin Chen

Abstract read
In one paragraph

Article in Emerging microbes & infections, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yingyin LiaoDepartment of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China.
Jiayan LiuDepartment of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China.
Pui WangDepartment of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China.
Bobo Wing-Yee MokDepartment of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China.ORCID 0000-0003-3187-2736
Honglin ChenDepartment of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China.ORCID 0000-0001-5108-8338

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Influenza A virus replication requires precise balance between unspliced and spliced viral mRNAs. However, the regulatory mechanisms governing viral mRNA splicing remain poorly understood. In this study, we uncover an epigenetic strategy whereby the viral NS1 protein autoregulates its own mRNA splicing via

Indexed as

AdenosineInfluenza A virusRNA, MessengerRNA SplicingRNA, ViralViral Nonstructural ProteinsAnimalsHumansInfluenza, HumanNerve Tissue ProteinsRNA-Binding ProteinsRNA Splicing FactorsSerine-Arginine Splicing FactorsVirus ReplicationAdenosineINS1 protein, influenza virusNerve Tissue ProteinsN-methyladenosineRNA-Binding ProteinsRNA, MessengerRNA Splicing FactorsRNA, ViralSerine-Arginine Splicing FactorsSRSF3 protein, humanViral Nonstructural ProteinsYTHDC1 protein, humanepitranscriptomicsInfluenza virusM6A modificationNS1viral mRNA splicing

Identifiers

PMID41066792
PMCPMC12557831

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.