Evidence map›Paper›PMID 41066674›Full record

ArticleAge and ageing2025

A novel electronic-health-record based, machine-learning model to predict 1-year risk of fall hospitalisation in older adults: a Hong Kong territory-wide cohort and modelling study.

Aimin Yang, Mai Shi, Eric S H Lau, Jiazhou Yu, Andrea O Y Luk, Ronald C W Ma, Alice P S Kong, Raymond Wong, Jones C M Chan, Juliana C N Chan and 1 more

Abstract read
In one paragraph

Article in Age and ageing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Aimin YangDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region, China.ORCID 0000-0003-2968-1762
Mai ShiDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region, China.
Eric S H LauDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region, China.
Jiazhou YuDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region, China.
Andrea O Y LukDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region, China.
Ronald C W MaDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region, China.
Alice P S KongDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region, China.
Raymond WongDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region, China.
Jones C M ChanDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region, China.
Juliana C N ChanDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region, China.
Elaine ChowDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region, China.

Funding

Chinese University of Hong Kong (CUHK) Impact-Research-Fellowship Scheme
6 · The paper itself

Abstract

objectiveOlder adults face high risk of falls. We developed an electronic-health-record (EHR) based machine-learning (ML) model to predict 1-year risk of fall in older adults for pre-emptive intervention.

methodsWe included 4 902 161 records from 1 142 000 adults aged ≥65 years who attended the Hong Kong Hospital Authority (HA) facilities in 2013-2017. We included 260 predictors including demographics, in-patient/out-patient admissions, emergency department (ED) attendance, complications, medications and laboratory tests during 1-year period to predict fall events based on diagnostic codes in the ensuing 12 months. The cohort was randomly split into training, testing and internal validation sets in a 7:2:1 ratio. We evaluated the performance of six ML-algorithms.

results67 163 fall events were accrued with the XGBoost model having the best performance in the validation set (area-under-the-receiver-operating-characteristic-curve [AUROC] = 0.979, area-under-the-precision-recall-curve [AUPRC] = 0.764; positive-predictive-value [PPV] = 0.614) versus logistic-regression model (AUROC = 0.885, AUPRC = 0.169; PPV = 0.210). The top 30 predictors included number of ED attendance, fasting plasma glucose, number and types of outpatient appointments, ED triage category of 'urgent', number of admissions and stay, age, residential districts, history of fall and medication use with an AUROC of 0.939 in a validation cohort of patients with diabetes. In an age- and sex-matched sub-cohort, compared to the widely-used Morse Fall Score, XGBoost model had higher sensitivity (0.569-versus-0.139) with optimal balance of identifying positive cases whilst simultaneously minimising false positives and false negative (F1 score: 0.626-versus-0.555).

conclusionsOur ML-model highlights the utility of EHR in identifying high-risk individuals for falls, supporting integrating into the EHR system for targeted preventive actions.

Indexed as

Accidental FallsElectronic Health RecordsHospitalizationMachine LearningAgedAged, 80 and overAge FactorsFemaleHong KongHumansMaleRisk AssessmentRisk Factorselectric health recordsfallmachine learningolder adultsrisk prediction

Identifiers

PMID41066674
PMCPMC12510402

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.