Evidence map›Paper›PMID 41066505›Full record

ArticlePLoS neglected tropical diseases2025

Barriers to rabies control through mass dog vaccination in rural Uganda: Insights from community perspectives and key informant interviews.

Dickson Akankwatsa, Arthur Bagonza, Juliet Kiguli, Andrew Kambugu, Mohammed Lamorde, Samuel George Okech, Clovice Kankya, Doreen Agado, Felister Apio, Terence Odoch and 6 more

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Dickson AkankwatsaDepartment of Community Health and Behavioral Sciences, Makerere University College of Health Sciences, School of Public Health, Kampala, Uganda.ORCID 0009-0007-6627-9058
Arthur BagonzaDepartment of Community Health and Behavioral Sciences, Makerere University College of Health Sciences, School of Public Health, Kampala, Uganda.
Juliet KiguliDepartment of Community Health and Behavioral Sciences, Makerere University College of Health Sciences, School of Public Health, Kampala, Uganda.
Andrew KambuguDepartment of Global Health Security, Infectious Diseases Institute, Makerere University, Kampala, Uganda.
Mohammed LamordeDepartment of Global Health Security, Infectious Diseases Institute, Makerere University, Kampala, Uganda.
Samuel George OkechDepartment of Veterinary Pharmacy, Clinical and Comparative Medicine, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
Clovice KankyaDepartment of Biosecurity, Ecosystems and Veterinary Public Health, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
Doreen AgadoDepartment of Biosecurity, Ecosystems and Veterinary Public Health, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
Felister ApioDepartment of Biosecurity, Ecosystems and Veterinary Public Health, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
Terence OdochDepartment of Biosecurity, Ecosystems and Veterinary Public Health, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
Anna Mary KahundeDepartment of Production Kyegegwa District Local Government, Kyegegwa, Uganda.
Sonja HartnackSection of Epidemiology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
Monique LéchenneSwiss Tropical and Public Health Institute, Swiss Center for International Health, Allschwil, Switzerland.
Frederic LohrWorldwide Veterinary Service, Cranborne, United Kingdom.
Adrian HerreraVeterinary Public Health Institute, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Salome DürrVeterinary Public Health Institute, Vetsuisse Faculty, University of Bern, Bern, Switzerland.

Funding

Swiss National Science Foundation
6 · The paper itself

Abstract

backgroundGlobally, rabies claims about 59,000 human lives annually, and 99% of human transmission is by dogs. The disease is entirely preventable through mass dog vaccination. Despite this, only an estimated 10% of dogs in Uganda are vaccinated, and the reasons for this low uptake are not fully understood. This study investigated barriers to mass dog vaccination for rabies control in Kyegegwa, a rural Ugandan district. METHODOLOGY: This qualitative study was conducted with eight key informants (KIs) and twelve focus groups (FGs) with participants from twelve randomly selected parishes. Audio recordings were transcribed in English and transcripts were managed using Atlas ti version 6.0 data management software. Thematic analysis was conducted to produce the results.

resultsThis study identified three major themes affecting mass dog vaccination in Kyegegwa District: (1) community dynamics, including misconceptions about vaccines, limited awareness, and difficulties in handling aggressive dogs; (2) Resource and service constraints such as vaccine shortages, limited veterinary personnel, and high costs; and (3) Systemic and operational challenges, including delayed campaign announcements, poor communication, and lack of vaccination certificates. These barriers collectively explain the persistently low coverage of mass dog vaccination in rural Uganda.

conclusionLimited awareness, logistical challenges, and inadequate veterinary resources were reported to be barriers to rabies control in Kyegegwa District. Addressing these issues may require timely communication, workforce strengthening, animal mobile clinics, and cost mitigation. Accurate dog population assessments and tailored community strategies may improve vaccination coverage, offering a foundation for effective rabies prevention in Kyegegwa District and similar resource-limited settings.

Indexed as

Dog DiseasesMass VaccinationRabiesRabies VaccinesAdultAnimalsDogsFemaleFocus GroupsHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedRural PopulationUgandaVaccinationRabies Vaccines

Identifiers

PMID41066505
PMCPMC12520382

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.