Evidence map›Paper›PMID 41066327›Full record

ArticlePLOS global public health2025

Preferences for long-acting injectable HIV pre-exposure prophylaxis service delivery among male and female sex workers in Uganda: A discrete choice experiment.

Richard Muhindo, Rachel King, Andrew Mujugira, Whitney Irie, Patience Muwanguzi, Flavia Dhikusooka, Joseph Musaazi, Barbara Castelnuovo

Abstract read
In one paragraph

Article in PLOS global public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Richard MuhindoDepartment of Nursing, College of Health Sciences, Makerere University, Kampala, Uganda.ORCID https://orcid.org/0000-0002-3249-117X
Rachel KingDepartment of Epidemiology and Biostatistics, University of California, San Francisco, California, United States of America.
Andrew MujugiraThe Infectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.ORCID https://orcid.org/0000-0001-6646-6733
Whitney IrieSchool of Social Work, Boston College, Chestnut Hill, Massachusetts, United States of America.
Patience MuwanguziDepartment of Nursing, College of Health Sciences, Makerere University, Kampala, Uganda.
Flavia DhikusookaThe Infectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
Joseph MusaaziThe Infectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
Barbara CastelnuovoThe Infectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.

Funding

University of California Launching Future Leaders in Global Health Research Training ProgramD43TW009343 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CRAIG R COHEN, Sung-Jae Lee · 2017 to 2026
$14.7M
FIC NIH HHS D43 TW009343
6 · The paper itself

Abstract

In Sub-Saharan Africa, limited data exist on the delivery of injectable HIV pre-exposure prophylaxis (PrEP). We explored service delivery preferences for injectable cabotegravir (CAB-LA) among heterosexual male sex workers (MSWs) and female sex workers (FSWs) in Uganda. We conducted a discrete choice experiment (DCE) among HIV-negative sex workers in two high HIV-prevalence Ugandan cities between October and December 2024. Participants selected from alternatives varying by location, waiting time, provider gender, and additional services. A mixed logit model identified the most valued attributes influencing preferences for CAB-LA delivery. We enrolled 251 sex workers (SWs), comprising 52 (20.7%) MSWs. MSWs were more likely to have higher education (26.9% vs 4.5%), while FSWs had been in the industry longer (24 months vs 18 months). PrEP awareness was lower among MSWs than FSWs (86.5% vs. 95.5%, p = 0.027). Overall, 39.4% reported current PrEP use. Injectable PrEP was the most preferred formulation (77.3%), and willingness to use PrEP among non-users was higher in MSWs (67.3% vs. 45.7%, p = 0.001). Regarding service delivery preferences, MSWs and FSWs both prioritized dispensing location (relative importance 81.1% MSWs, 82.9% FSWs) and provision of additional services (10.8% MSWs, 9% FSWs). In contrast, clinic waiting time and provider gender were considered the least important, with both groups assigning them a relative importance of 4%. Nevertheless, the three top-ranked CAB-LA delivery models prioritized access through private pharmacies or clinics with short waiting times, female or peer providers, and integrated health services. The preferred extra services included psychosocial support, cancer screening, and risk reduction counseling. Expanding injectable PrEP through private sector channels may improve access among SWs. Still, implementation research is needed to guide integration of supportive services and SWs' willingness to pay or co-pay for pharmacy or private clinic-based delivery.

Identifiers

PMID41066327
PMCPMC12510523

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.