Evidence map›Paper›PMID 41066077›Full record

ArticleTransfusion medicine (Oxford, England)2026

Quality of platelet concentrates after three-day storage following 265 nm ultraviolet C-light-emitting diode irradiation.

Tomoya Hayashi, Yoshihiko Sakurai, Yoshihiro Fujimura, Kumiko Oguma, Yuichi Mishima, Fumiya Hirayama, Yoshihiko Tani, Yoshihiro Takihara, Takafumi Kimura

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In one paragraph

Article in Transfusion medicine (Oxford, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tomoya HayashiDepartment of Research and Development, Japanese Red Cross Kinki Block Blood Center, Japanese Red Cross Society, Osaka, Ibaraki, Japan.ORCID https://orcid.org/0000-0002-1776-0052
Yoshihiko SakuraiDepartment of Research and Development, Japanese Red Cross Kinki Block Blood Center, Japanese Red Cross Society, Osaka, Ibaraki, Japan.ORCID https://orcid.org/0000-0002-1773-5535
Yoshihiro FujimuraDepartment of Research and Development, Japanese Red Cross Kinki Block Blood Center, Japanese Red Cross Society, Osaka, Ibaraki, Japan.ORCID https://orcid.org/0000-0002-4887-5741
Kumiko OgumaDepartment of Urban Engineering, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0001-5152-6553
Yuichi MishimaJapanese Red Cross Society, Central Blood Institute, Tokyo, Japan.
Fumiya HirayamaDepartment of Research and Development, Japanese Red Cross Kinki Block Blood Center, Japanese Red Cross Society, Osaka, Ibaraki, Japan.ORCID https://orcid.org/0000-0001-6518-2085
Yoshihiko TaniJapanese Red Cross Society, Central Blood Institute, Tokyo, Japan.ORCID https://orcid.org/0000-0003-0294-6062
Yoshihiro TakiharaDepartment of Research and Development, Japanese Red Cross Kinki Block Blood Center, Japanese Red Cross Society, Osaka, Ibaraki, Japan.
Takafumi KimuraDepartment of Research and Development, Japanese Red Cross Kinki Block Blood Center, Japanese Red Cross Society, Osaka, Ibaraki, Japan.ORCID https://orcid.org/0000-0002-8718-2024

Funding

Japanese red cross society -24
6 · The paper itself

Abstract

objectivesWe aimed to investigate the quality of platelets after storage following irradiation with ultraviolet C (UVC) light-emitting diodes (LED).

backgroundControlling transfusion-related infections, particularly bacterial contamination of platelet concentrates (PCs), is urgently required. UVC-LEDs have attracted considerable attention as potential solutions to this problem.

methodsPCs (5.5 mL) were irradiated with 265 nm UVC-LED for up to 60 min and then stored at 22°C with shaking for 3 days. PC quality parameters, such as platelet count, biochemical profiles, including electrolytes and metabolism, activation markers and platelet aggregability, were analysed before and after storage. Prior to the storage study, to validate the appropriateness of the UVC-LED dose used, the PCs were inoculated with Staphylococcus aureus or Bacillus cereus, and their colony-forming ability was evaluated after irradiation with the same dose of UVC-LED.

resultsWe confirmed that S. aureus and B. cereus colonies decreased with the irradiation dose (by 1.7 log and 1.2 log at 38.7 and 40.4 mJ cm

conclusionThese results indicate that UVC-irradiated platelets maintain sufficient quality for practical use even after storage. Although this was a bench-scale study, our findings suggest that irradiation of PCs with 265 nm UVC-LED may enhance the safety of blood transfusions while preserving their efficacy.

Indexed as

Blood PlateletsBlood PreservationUltraviolet RaysBacillus cereusHumansPlatelet CountStaphylococcus aureusTime Factors265 nm ultravioletLEDplatelet concentratequality assessmentstorage

Identifiers

PMID41066077
PMCPMC12882763

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.