Evidence map›Paper›PMID 41066026›Full record

ArticleAnnals of nuclear medicine2026

Use of the tracheal bisecting line to differentiate upper pole from lower pole parathyroid adenomas: a PET/MR study using [

Junko Inoue Inukai, Bert-Ram Sah, Stephan Beintner-Skawran, Alexander Maurer, Simon A Mueller, Grégoire B Morand, Munenobu Nogami, Takamichi Murakami, Niels J Rupp, Petra Petranović Ovčariček and 2 more

Abstract read
In one paragraph

Article in Annals of nuclear medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Challenges and unmet needs of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Junko Inoue InukaiDepartment of Nuclear Medicine, University Hospital Zurich and University of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland. inouej@med.kobe-u.ac.jp.
Bert-Ram SahDepartment of Nuclear Medicine, University Hospital Zurich and University of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.
Stephan Beintner-SkawranDepartment of Nuclear Medicine, University Hospital Zurich and University of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.
Alexander MaurerDepartment of Nuclear Medicine, University Hospital Zurich and University of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.
Simon A MuellerDepartment of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zurich and University of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.
Grégoire B MorandDepartment of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zurich and University of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.
Munenobu NogamiDepartment of Radiology, Kobe University Graduate School of Medicine, 7-5-1, Kusunoki-Cho, Chuo-Ku, KobeHyogo, 650-0017, Japan.
Takamichi MurakamiDepartment of Radiology, Kobe University Graduate School of Medicine, 7-5-1, Kusunoki-Cho, Chuo-Ku, KobeHyogo, 650-0017, Japan.
Niels J RuppDepartment of Pathology and Molecular Pathology, University Hospital Zurich and University of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.
Petra Petranović OvčaričekDepartment of Nuclear Medicine, University Hospital Zurich and University of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.
Luca GiovanellaDepartment of Nuclear Medicine, University Hospital Zurich and University of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.
Martin W HuellnerDepartment of Nuclear Medicine, University Hospital Zurich and University of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAccurate preoperative localization of parathyroid adenomas is crucial in managing primary hyperparathyroidism (pHPT). Although [

methodsThis retrospective study included 110 patients (128 adenomas) with biochemically confirmed pHPT who underwent [

resultsAmong the 128 adenomas, 109 were orthotopic and 19 non-orthotopic (6 intrathyroidal). The inter-reader agreement was nearly perfect (κ = 0.99). The overall accuracy using the TBL was 0.945. The accuracy improved to 0.982 for orthotopic adenomas but decreased to 0.789 for non-orthotopic and 0.667 for intrathyroidal cases. Excluding intrathyroidal adenomas raised accuracy to 1.0 in non-orthotopic cases and 0.959 overall for non-intrathyroidal adenomas.

conclusionsThe TBL is a reliable and reproducible landmark on [

Indexed as

AdenomaCholineMagnetic Resonance ImagingParathyroid NeoplasmsAdultAgedDiagnosis, DifferentialFemaleHumansMaleMiddle AgedPositron-Emission TomographyRetrospective StudiesCholinefluorocholineFluorocholineHyperparathyroidismParathyroid glandsPositron emission tomography/computed tomographyPositron emission tomography/magnetic resonance imagingTrachea

Identifiers

PMID41066026
PMCPMC12789206

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.