Evidence map›Paper›PMID 41065996›Full record

ArticleInfection2026

Pivotal plasmids drive the global spread of CTX-M-27 in Escherichia coli.

Yan Zhang, Yexin Lin, Yingxin Ruan, Jintao Yang, Emma Holden, Heather Felgate, Maria Solsona, Hoyu Liu, Guan Liang, Hongxia Jiang and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Genomic Diversity and Extended-SpectrumInternational journal of microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yan Zhang *Department of Infection, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, Guangzhou, China.
Yexin Lin *Department of Infection, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, Guangzhou, China.
Yingxin Ruan *Department of Nephrology, Kidney Disease Medical Center, General Hospital, Tianjin Medical University, National Key Clinical Specialty, Tianjin Key Medical Discipline, Tianjin, China.
Jintao YangGuangdong Key Laboratory for Veterinary Pharmaceutics Development and Safety evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Emma HoldenQuadram Institute Bioscience, Norwich, United Kingdom.
Heather FelgateQuadram Institute Bioscience, Norwich, United Kingdom.
Maria SolsonaQuadram Institute Bioscience, Norwich, United Kingdom.
Hoyu LiuQuadram Institute Bioscience, Norwich, United Kingdom.
Guan LiangGuangdong Laboratory for Lingnan Modern Agriculture, South China Agricultural University, Guangzhou, China.
Hongxia Jiang *Guangdong Key Laboratory for Veterinary Pharmaceutics Development and Safety evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China. hxjiang@scau.edu.cn.
Mark A Webber *Quadram Institute Bioscience, Norwich, United Kingdom. Mark.Webber@quadram.ac.uk.
Chao Zhuo *Department of Infection, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, Guangzhou, China. chaosheep@gzhmu.edu.cn.

Funding

the National Natural Science Foundation of China 82172318
6 · The paper itself

Abstract

The detection rate of CTX-M-27-producing E. coli has increased worldwide in recent years although relatively little is known about the strains and vectors responsible for this increased isolation.To explore the evolution of CTX-M-27-producing E. coli in the past 20 years at three levels; genetic structure of the bla

Indexed as

beta-LactamasesEscherichia coliEscherichia coli InfectionsEscherichia coli ProteinsPlasmidsGenome, BacterialGlobal HealthHumansVirulence Factorsbeta-LactamasesCTX-M-27, E coliEscherichia coli ProteinsVirulence FactorsAntimicrobial resistancebla CTX−M−27ESBLsEvolutionHorizontal gene transferPlasmidST131

Identifiers

PMID41065996
PMCPMC12864245

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.