Evidence map›Paper›PMID 41065944›Full record

ReviewMedicine, health care, and philosophy2026

The ethics of Wegovy: promoting autonomy in pediatric care.

Nanette Ryan, Julian Savulescu

Abstract readReview
In one paragraph

Review in Medicine, health care, and philosophy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nanette RyanCentre for Biomedical Ethics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.ORCID http://orcid.org/0009-0007-7540-149X
Julian SavulescuCentre for Biomedical Ethics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. jsavules@nus.edu.sg.ORCID http://orcid.org/0000-0003-1691-6403

Funding

NUHS Internal Grant Funding NUS Start-up Grant/NUHSRO/2022/078/Startup/13NUHS Internal Grant Funding Startup Grant/NUHSRO/2020/138/Startup/07Wellcome Trust 226801
6 · The paper itself

Abstract

Semaglutide, marketed as Wegovy, Ozempic, and Rybelsus, is a glucagon-like peptide-1 receptor agonist (GLP-1 RA) that has attracted significant global attention for its appetite-suppressing and weight-loss effects. Approved for pediatric use in children aged 12 and older, Wegovy has been described as a "miracle drug" and hailed as a potential solution to the so-called "obesity epidemic." However, prescribing medication to children raises complex ethical questions, including how best to respect young patients' autonomy and promote their well-being. This paper focuses on one such concern: the "argument from virtue." According to this view, Wegovy represents a morally problematic approach to weight loss because it circumvents the development of character traits-such as self-control and resilience-that are seen as integral to autonomy. We critically examine this argument, rejecting the claim that there is a single morally "right way" to lose weight, and argue that Wegovy, when prescribed within a supportive framework, may help children build and exercise autonomy. We review the drug's function and efficacy, analyze how it might promote or hinder autonomy, and offer recommendations to support ethical prescribing practices that align with respect for children's agency.

Indexed as

PediatricsPersonal AutonomyChildHumansWeight LossAutonomyChildrenEthicsObesityOzempicPaediatricsWegovyWeight-loss

Identifiers

PMID41065944
PMCPMC12960309

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.