ArticleNetherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation2025
Longitudinal results from a dedicated chronic total coronary occlusions percutaneous coronary intervention program-a single-center experience.
Article in Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Persistent high major adverse cardiac outcome of 7% with chronic total occlusion intervention in patients with stable coronary artery disease.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2026Article
- Advancing cardiovascular care-key insights from the Netherlands Heart Journal 2025.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2026Article
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Authors and funding
15 authors.
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Abstract
objectiveTo provide insight into the longitudinal (> 10 years) results of a dedicated CTO PCI program in a single center.
backgroundPercutaneous coronary intervention (PCI) of chronic total occlusions (CTO) requires substantial operator experience. Dedicated CTO programs aim to increase technical success rates through sufficient case volume. However, longitudinal data beyond 10 years on such programs are scarce.
methodsWe included 1185 patients who underwent CTO PCI in the Amsterdam University Medical Center between 2013 and 2024. Technical CTO PCI success was defined as thrombolysis in myocardial infarction flow grade 3 and < 30% residual stenosis. Procedural success was defined as technical success in the absence of in-hospital major adverse cardiovascular events. Multivariable logistic regression analyses were used to identify predictors for technical success.
resultsMean age was 66 ± 11 years; 81% were male. Overall technical CTO PCI success (92%) and procedural success (87%) rates were high and consistent. We observed temporal changes in wire crossing time (31 [7-56] to 23 [5-67] minutes), contrast volume (360 ± 160 to 210 ± 101 mL), and procedural time (90 [60-130] to 121 [80-165] minutes). Additionally, MACE rate improved from 13% (in 2013-2015) to 7% (in 2021-2024). Age ≥ 65 years, prior CABG, three-vessel disease, and an intermediate to high J‑CTO score (≥ 2) predicted technical failure.
conclusionsThis study reports the longitudinal (> 10 years) results of a dedicated CTO PCI program, which confirms that high technical CTO PCI and procedural success rates can be achieved by a single center.
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