Evidence map›Paper›PMID 41065912›Full record

ArticleAMB Express2025

Fermentation process optimization of a bacteriostatic Bacillus coagulans based on response surface methodology.

Yonghong Li, Xiuxiu Wu, Min Li, Xuan Li, Jian Wang, Keke Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AMB Express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yonghong LiSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Xiuxiu WuSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Min LiSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Xuan LiSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Jian WangSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Keke LiHeNanJinBaiHe Biotechnology Co., LTD, Anyang, 450000, Henan, China. likeke202201@163.com.

Funding

Henan Provincial Science and Technology Research Project No.:Z20221343015
6 · The paper itself

Abstract

Bacillus coagulans is a spore-producing lactic acid bacterium with strong stress resistance. It has been widely used in food preservation, food fermentation, livestock diarrhea prevention, medication-assisted treatment, pollutant removal et al. In the study, a Bacillus coagulans strain with superior inhibition on Staphylococcus aureus, Escherichia coli, Vibrio parahaemolyticus and Aeromonas hydrophila was screened. Its medium composition and culture conditions were optimized in flasks using single factor experiment, Plackett Burman experiment, minimum addition experiment and response surface analysis experiment. The optimal medium composition was determined to be 14.64 g/L molasses, 0.4848 g/L MgSO

Indexed as

Bacillus coagulansBacteriostatic activityFermentation process optimizationResponse surface analysis

Identifiers

PMID41065912
PMCPMC12511497

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.