Evidence map›Paper›PMID 41065784›Full record

ArticleUrologie (Heidelberg, Germany)2026

[Self-critical, multicenter analysis of treatment and coding quality using the example of nephroureterectomy on the basis of billing data].

Nici Markus Dreger, Christine Lenhart, Friedrich-Carl von Rundstedt, Thomas Steiner, Mark Schrader, Chris Protzel, Martin Friedrich, Wolfgang Jäger, Frank Vom Dorp, Alexander Roosen and 3 more

Abstract readMulticenter StudyEnglish Abstract
In one paragraph

Article in Urologie (Heidelberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Nici Markus DregerHelios Universitätsklinikum Wuppertal, Heusnerstr. 40, 42283, Wuppertal, Deutschland.
Christine LenhartFakultät für Gesundheit, Private Universität Witten/Herdecke, Witten/Herdecke, Deutschland.
Friedrich-Carl von RundstedtHelios Universitätsklinikum Wuppertal, Heusnerstr. 40, 42283, Wuppertal, Deutschland. friedrich.vonrundstedt@helios-gesundheit.de.
Thomas SteinerHelios Klinikum Erfurt, Erfurt, Deutschland.
Mark SchraderHelios Klinikum Berlin-Buch, Berlin, Deutschland.
Chris ProtzelHelios Klinikum Schwerin, Schwerin, Deutschland.
Martin FriedrichHelios Klinikum Krefeld, Krefeld, Deutschland.
Wolfgang JägerHelios Klinikum Wiesbaden, Wiesbaden, Deutschland.
Frank Vom DorpHelios Klinikum Duisburg, Duisburg, Deutschland.
Alexander RoosenHelios Klinikum Velbert, Velbert, Deutschland.
Olaf ReicheltHelios Klinikum Aue, Aue, Deutschland.
Sven HohensteinHelios Health Institute GmbH, Berlin, Deutschland.
Stephan DegenerHelios Universitätsklinikum Wuppertal, Heusnerstr. 40, 42283, Wuppertal, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUrothelial carcinomas of the upper urinary tract (UTUC) are rare, accounting for approximately 5-10% of all urothelial carcinomas. In contrast to urothelial carcinomas of the bladder, UTUCs are often invasive at the time of diagnosis. Radical nephroureterectomy (RNU) is the gold standard for treatment, with minimally invasive procedures gaining increasing importance. Aim of this study was to examine the development of RNU in terms of case numbers, surgical methods, treatment quality, and guideline adherence. MATERIALS AND

methodsThis study is based on a retrospective analysis of German Diagnosis-Related Groups (G-DRG) billing data from 87 Helios hospitals in Germany for the period 2016-2022. Patients with a primary diagnosis of UTUC who had undergone RNU were included. Surgical procedures were classified as open surgery or minimally invasive (laparoscopic or robot-assisted). Various parameters such as length of hospital stay (LOS), complications and postoperative interventions were analyzed. A post hoc survey of the clinics served to validate billing data.

resultsA total of 594 patients underwent RNU. The proportion of robot-assisted RNU steadily increased, while open procedures decreased. Minimally invasive procedures resulted in shorter hospital stays (9.9 days vs. 12.3 days; p < 0.001), fewer complications such as anemia due to bleeding (12% vs. 26%), and a decreasing need for intensive care (57% vs. 71%; p < 0.001). Bladder cuff resection was less frequently performed in minimally invasive RNU (6.6% vs. 46%; p < 0.001). However, intravesical instillation of chemotherapeutic agents was only performed in a small proportion of patients regardless of surgical method (10% vs. 6.9%; p = 0.116), although the post hoc survey revealed a coding bias and showed a cuff resection rate of 92% and an instillation rate of 52%.

conclusionRobotic surgeries demonstrated significant advantages with regard to hospital stay and complications. However, insufficient guideline adherence was noted regarding postoperative instillation, highlighting points for improvement. The analysis shows a clear discrepancy (real-world evidence gap) between coded DRG data and actual clinical care. This disparity influences key structural and service decisions in the German healthcare system and must be urgently taken into account when interpreting administrative datasets.

Indexed as

Carcinoma, Transitional CellClinical CodingKidney NeoplasmsNephroureterectomyUreteral NeoplasmsAgedFemaleGermanyGuideline AdherenceHumansLength of StayMaleMiddle AgedRetrospective StudiesRobotic Surgical ProceduresCoronavirus disease 2019COVID-19 pandemicGuideline adherenceReal world evidence gapUpper tract urothelial carcinoma

Identifiers

PMID41065784
PMCPMC12979303

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.