Evidence map›Paper›PMID 41065631›Full record

SynthesisThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2025

Just-in-Time Adaptive Interventions for Adolescent and Young Adult Substance Use: A Systematic Review.

Camila Koike, Bridget A Nestor, Pelin S Gelmez, Anne Fladger, Lydia A Shrier, Joe Kossowsky

Abstract readSystematic Review
In one paragraph

Synthesis in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Observational
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Camila KoikeDepartment of Anesthesiology, Critical Care, and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts; Department of Anesthesia, Harvard Medical School, Boston, Massachusetts.
Bridget A NestorDepartment of Anesthesiology, Critical Care, and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts; Department of Anesthesia, Harvard Medical School, Boston, Massachusetts; Department of Psychology, Endicott College, Beverly, Massachusetts.
Pelin S GelmezDepartment of Psychology, University of Zurich, Zurich, Switzerland.
Anne FladgerCountway Library of Medicine, Harvard Medical School, Boston, Massachusetts.
Lydia A ShrierDivision of Adolescent and Young Adult Medicine, Boston Children's Hospital, Boston, Massachusetts; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts.
Joe KossowskyDepartment of Anesthesiology, Critical Care, and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts; Department of Anesthesia, Harvard Medical School, Boston, Massachusetts. Electronic address: joe.kossowsky@childrens.harvard.edu.

Funding

Mobile health applications in adolescent marijuana use: assessing the interplay among sleep, pain and inhibitory control - SupplementK01DA057374 · NIDA · BOSTON CHILDREN'S HOSPITAL · PI Joe Kossowsky · 2023 to 2026
$811k
NIDA NIH HHS K01 DA057374
6 · The paper itself

Abstract

This systematic review examines the characteristics, feasibility, acceptability, and efficacy of just-in-time adaptive interventions (JITAIs) for adolescent and young adult (AYA) substance use. A systematic search identified studies published between January 2000 and September 2023 using terms related to substance use, AYA, and JITAI. Peer-reviewed studies reporting data on JITAIs for substance use in AYA (ages 13-25) were included. Intervention elements, substance type, feasibility, acceptability, and efficacy outcomes were extracted. Of 6,755 screened titles and abstracts, six studies with 168 participants met eligibility. Targeted substances included alcohol (k = 1), tobacco (k = 1), cannabis (k = 2), and polysubstance use (k = 2). All studies used ecological momentary assessment. Intervention timing varied: three studies used prespecified time intervals, two used random times, and one delivered messages at a fixed daily time. Content emphasized goal-relevant feedback, motivational interviewing, and self-efficacy enhancement. Participants generally found interventions engaging, with adequate retention and compliance rates. Our findings support preliminary JITAI efficacy, with three studies reporting significant substance use reductions during the intervention and two reporting significant reductions compared to control groups. JITAIs also appear feasible and acceptable for AYA substance use. JITAI research is still underdeveloped in the scientific literature. Future research should explore moderating factors of JITAI efficacy, engagement strategies to improve adherence, and establish a consistent JITAI definition.

Indexed as

Motivational InterviewingSubstance-Related DisordersAdolescentAdultFemaleHumansMaleSelf EfficacyYoung AdultAdolescents and young adultsJust-in-time adaptive interventionsSubstance use

Identifiers

PMID41065631
PMCPMC12614282

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.