ArticleMolecular nutrition & food research2025
Peptides From Adzuki Bean and Soybean Improved Insulin-AKT Signaling-Related Pathways in Healthy and Insulin-Resistant States in Human Liver Cells.
Article in Molecular nutrition & food research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Food-Derived Antidiabetic Peptides as Multi-Target Systemic Regulators: A Comprehensive Review of Sources, Preparation, Mechanisms and Future Perspectives.Foods (Basel, Switzerland) · 2026Review
- Peptides From Adzuki Bean and Soybean Improved Insulin-AKT Signaling-Related Pathways in Healthy and Insulin-Resistant States in Human Liver Cells.Molecular nutrition & food research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The objectives were to determine the effect and mechanism of functional peptides identified from digested adzuki bean β-vignin and soybean β-conglycinin on insulin-AKT signaling and hepatic glucose uptake markers and to investigate the roles of these peptides in modulating the insulin-AKT signaling pathway in human liver cells in healthy and insulin-resistant states. Methods and Results: Adzuki bean β-vignin and soybean β-conglycinin proteins were isolated and digested using simulated gastrointestinal digestion. Peptide sequences (VP, PM, FNE, LLS, and IPA), in silico analysis and in vitro (cell-free and HepG2 cell-based) systems confirmed their safety and dipeptidyl peptidase IV (DPP IV) inhibitory capacity. IPA and VP showed high intestinal absorption and low toxicity, inhibited DPP IV (IPA IC
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.