Evidence map›Paper›PMID 41065250›Full record

ArticleJournal of the American Heart Association2025

Listing for Pediatric Donation After Circulatory Death Heart Transplantation Is Associated With Improved Waitlist Outcomes.

Michael A Catalano, Max Shin, Omar Toubat, Radhika Rastogi, Halil Beqaj, Amit Iyengar, Benjamin F Smood, Nikia Toomey, Jonathan B Edelson, Joseph W Rossano and 5 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Michael A CatalanoDivision of Cardiac Surgery University of Pennsylvania Philadelphia PA USA.ORCID 0000-0001-8656-6352
Max ShinDivision of Cardiac Surgery University of Pennsylvania Philadelphia PA USA.ORCID 0000-0002-2748-3052
Omar ToubatDivision of Cardiac Surgery University of Pennsylvania Philadelphia PA USA.
Radhika RastogiDivision of Cardiology Children's Hospital of Philadelphia Philadelphia PA USA.ORCID 0000-0003-1313-6620
Halil BeqajDivision of Cardiac Surgery University of Pennsylvania Philadelphia PA USA.ORCID 0000-0002-7980-7549
Amit IyengarDivision of Cardiac Surgery University of Pennsylvania Philadelphia PA USA.ORCID 0000-0001-7689-1733
Benjamin F SmoodDivision of Cardiac Surgery University of Pennsylvania Philadelphia PA USA.ORCID 0000-0002-8667-6591
Nikia ToomeyDivision of Cardiac Surgery Children's Hospital of Philadelphia Philadelphia PA USA.ORCID 0000-0003-1749-3983
Jonathan B EdelsonDivision of Cardiology Children's Hospital of Philadelphia Philadelphia PA USA.ORCID 0000-0003-3220-7922
Joseph W RossanoDivision of Cardiology Children's Hospital of Philadelphia Philadelphia PA USA.ORCID 0000-0002-8284-0673
Matthew J O'ConnorDivision of Cardiology Children's Hospital of Philadelphia Philadelphia PA USA.ORCID 0000-0003-3012-5464
Humera AhmedDivision of Cardiology Children's Hospital of Philadelphia Philadelphia PA USA.ORCID 0000-0002-1572-4840
J William GaynorDivision of Cardiac Surgery Children's Hospital of Philadelphia Philadelphia PA USA.ORCID 0000-0001-7955-5604
Katsuhide MaedaDivision of Cardiac Surgery Children's Hospital of Philadelphia Philadelphia PA USA.ORCID 0000-0002-3087-6316
Constantine D MavroudisDivision of Cardiac Surgery University of Pennsylvania Philadelphia PA USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdvances in procurement techniques have enabled use of hearts obtained via donation after circulatory death (DCD), expanding the donor pool; however, the impact of DCD heart transplant on outcomes in children is not well described. We aim to characterize waitlist survival and outcomes in pediatric heart transplant candidates listed for donation after brain death (DBD) versus DCD hearts.

methodsThe United Network for Organ Sharing database was queried for patients aged <18 years at listing, waitlisted for heart transplant between January 2021 and June 2024. Patients were stratified by listing for DBD exclusively, versus DBD and DCD hearts. Waitlist and posttransplant outcomes were compared using Fine-Gray and Kaplan-Meier analyses.

resultsOf 2449 listed patients, 2353 (96.1%) were listed for DBD hearts exclusively, and 96 (3.9%) for DCD hearts as well. DCD recipient candidates had increased rates of cardiopulmonary support and were more likely to be status 1A. Of DCD recipient candidates, 15 (15.6%) received DCD hearts and 50 (52.1%) received DBD hearts. When controlling for status, extracorporeal membrane oxygenation, blood type, region, and year, DCD listing was not associated with likelihood of transplant or waitlist death. Among status 1B/2 patients, DCD listing was associated with increased likelihood of transplant (adjusted subhazard ratio, 2.05 [95% CI, 1.16-3.62];

conclusionsAmong candidates for pediatric heart transplant listed as status 1B/2, patients listed for DCD hearts in addition to DBD hearts have shorter waitlist duration, improved transplant rates, lower waitlist mortality rates, and comparable survival to patients listed for DBD hearts alone.

Indexed as

Heart TransplantationTissue and Organ ProcurementTissue DonorsWaiting ListsAdolescentBrain DeathChildChild, PreschoolDatabases, FactualFemaleHumansInfantMaleRetrospective StudiesTime FactorsTreatment Outcomedonation after circulatory deathpediatric heart transplantwaitlist survival

Identifiers

PMID41065250
PMCPMC12684558

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.