SynthesisInternational journal of rheumatic diseases2025
Effect of Pilates Exercise on Health-Related Outcomes in Patients With Knee Osteoarthritis: A Systematic Review and Meta-Analysis.
Synthesis in International journal of rheumatic diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effect of Pilates Exercise on Health-Related Outcomes in Patients With Knee Osteoarthritis: A Systematic Review and Meta-Analysis.International journal of rheumatic diseases · 2025Pooled it
- Effect of iPACK block versus femoral nerve block on postoperative movement pain and muscle strength in patients undergoing total knee replacement.American journal of translational research · 2026Article
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8 authors.
Funding
Abstract
introductionKnee osteoarthritis (KOA) is a chronic, progressive condition characterized by cartilage degeneration, synovial inflammation, and bone changes leading to pain and functional impairment. Despite the availability of various treatment options, including multidisciplinary approaches and muscle strengthening exercises, there remains uncertainty regarding the efficacy of Pilates as a therapeutic intervention for KOA. This highlights the need for a systematic review to synthesize current evidence on the effects of Pilates on health-related outcomes in this population.
objectiveThis systematic review aimed to analyze the effects of Pilates compared to no exercise or conventional exercises on pain in individuals with knee osteoarthritis, as well as on secondary outcomes including function, quality of life, range of motion, balance, and adverse events. A secondary aim is to characterize the key components and implementation characteristics of the Pilates interventions applied in the included studies.
methodsThe review protocol has been registered in PROSPERO under the number CRD42024532727. Searches were conducted in PubMed/MEDLINE, Embase, CINAHL, CENTRAL, Scopus, Web of Science, and SPORTDiscus. Eligible studies included randomized controlled trials (RCTs) that investigated the impact of Pilates exercises in patients aged ≥ 18 years, diagnosed with KOA according to the Kellgren and Lawrence criteria or the American College of Rheumatology. Studies including participants with systemic arthritis, knee joint surgery within the past 12 months, lower extremity arthroplasty, intra-articular steroid injections within the past 6 months, or any neurological conditions were excluded. The risk of bias was assessed using the RoB 2 tool, and the quality of evidence was evaluated using the GRADE approach. Meta-analyses used random-effects models, with standardized mean differences (SMDs) and heterogeneity analyzed using I
resultsEleven studies involving 476 participants were included, of which seven contributed to the quantitative synthesis. Based on this analysis, Pilates exercises reduced pain compared to no intervention (SMD -1.09; 95% CI -2.04 to -0.14; I
conclusionThe Pilates method may be an effective alternative for the rehabilitation of patients with KOA, particularly in reducing pain compared to no intervention. However, it did not demonstrate superiority over conventional exercises in pain reduction or knee health improvement. Pilates was more effective in increasing range of motion compared to conventional exercises and showed benefits in proprioception, dynamic balance, and quality of life. The heterogeneity among the studies and the low quality of the evidence suggests caution in the interpretation of the results, with new RCTs potentially impacting the findings of this review.
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