Evidence map›Paper›PMID 41064991›Full record

ArticleAngewandte Chemie (International ed. in English)2025

Aluminum Exposure Impairs Electrochemically Measured Vesicular Storage and Exocytosis via Iron Homeostasis Dysregulation.

Shi-Hua Chen, Chaoyi Gu, Xing-Jiu Huang, Andrew G Ewing

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shi-Hua ChenDepartment of Chemistry and Molecular Biology, University of Gothenburg, Medicinaregatan 19, Gothenburg, 41390, Sweden.
Chaoyi GuDepartment of Chemistry and Molecular Biology, University of Gothenburg, Medicinaregatan 19, Gothenburg, 41390, Sweden.
Xing-Jiu HuangKey Laboratory of Environmental Optics and Technology, And Environmental Materials and Pollution Control Laboratory, Institute of Solid State Physics, HFIPS, Chinese Academy of Sciences, Hefei, 230031, China.
Andrew G EwingDepartment of Chemistry and Molecular Biology, University of Gothenburg, Medicinaregatan 19, Gothenburg, 41390, Sweden.ORCID 0000-0002-2084-0133

Funding

European Research CouncilKnut and Alice Wallenberg FoundationSwedish Research Council (VR)
6 · The paper itself

Abstract

Widespread human exposure to aluminum (Al) has raised increasing concerns about its effects on neuronal functions since Al

Indexed as

AluminumExocytosisHomeostasisIronAnimalsDeferoxamineElectrochemical TechniquesFerric CompoundsHumansPC12 CellsRatsReceptors, TransferrinAluminumDeferoxamineFerric CompoundsIronReceptors, TransferrinAluminumCellular iron homeostasisExocytosisRelease fractionTransferrin

Identifiers

PMID41064991
PMCPMC12643330

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.