Evidence map›Paper›PMID 41064883›Full record

ArticleCirculation research2025

Cardiomyocyte-Restricted Expression of Progerin Confers Cardiac Hypertrophy.

Tuerdi Subati, Dennis P Buehler, Lin Zhong, Francis J Miller, Vineet Agrawal, Jonathan D Brown

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tuerdi SubatiDivision of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN (T.S., D.P.B., L.Z., F.J.M., V.A., J.D.B.).ORCID 0000-0001-7779-9277
Dennis P BuehlerDivision of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN (T.S., D.P.B., L.Z., F.J.M., V.A., J.D.B.).
Lin ZhongDivision of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN (T.S., D.P.B., L.Z., F.J.M., V.A., J.D.B.).ORCID 0000-0003-2550-3758
Francis J MillerDivision of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN (T.S., D.P.B., L.Z., F.J.M., V.A., J.D.B.).ORCID 0000-0001-5822-0549
Vineet AgrawalDivision of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN (T.S., D.P.B., L.Z., F.J.M., V.A., J.D.B.).ORCID 0000-0002-8457-6722
Jonathan D BrownDivision of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN (T.S., D.P.B., L.Z., F.J.M., V.A., J.D.B.).ORCID 0000-0002-0359-6167

Funding

Gene Therapy in Hutchinson-Gilford Progeria SyndromeR01HL160970 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BROWN, JONATHAN DAVID · 2022 to 2025
$2.9M
Elucidating the chromatin-dependent mechanisms governing chronic inflammatory activation of endothelial cells in atherosclerosis.R01HL146654 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BROWN, JONATHAN DAVID · 2020 to 2023
$2.4M
BLRD VA IK2 BX005828NHLBI NIH HHS R01 HL146654NHLBI NIH HHS R01 HL160970
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

agingheart failurehypertrophymyocytes, cardiacprogeria

Identifiers

PMID41064883
PMCPMC12739752

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.