Evidence map›Paper›PMID 41064676›Full record

ArticleThe Pan African medical journal2025

[HIV-pulmonary tuberculosis co-infection at the university clinics of Lubumbashi: epidemiological and clinical aspects].

Patrick Mutombo Tshibang, Georges Yumba Numbi, Eugénie Tshiami Bukasa, Evariste Yav Tshibind, Thierry Kisoka Kimbungu, Serge Ngoie Muleka

Abstract readEnglish Abstract
In one paragraph

Article in The Pan African medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Patrick Mutombo TshibangDépartement de Médecine Interne, Faculté de Médecine, Université de Lubumbashi, Lubumbashi, République Démocratique du Congo.
Georges Yumba NumbiDépartement de Médecine Interne, Faculté de Médecine, Université de Lubumbashi, Lubumbashi, République Démocratique du Congo.
Eugénie Tshiami BukasaDépartement de Médecine Interne, Faculté de Médecine, Université de Lubumbashi, Lubumbashi, République Démocratique du Congo.
Evariste Yav TshibindDépartement de Médecine Interne, Faculté de Médecine, Université de Lubumbashi, Lubumbashi, République Démocratique du Congo.
Thierry Kisoka KimbunguDépartement de Médecine Interne, Faculté de Médecine, Université de Lubumbashi, Lubumbashi, République Démocratique du Congo.
Serge Ngoie MulekaDépartement de Médecine Interne, Faculté de Médecine, Université de Lubumbashi, Lubumbashi, République Démocratique du Congo.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: this study aims to provide an overview of the epidemiological and clinical characteristics of HIV-pulmonary tuberculosis (TB) co-infection among patients treated at the University Clinics of Lubumbashi. Methods: we conducted a descriptive cross-sectional study based on the analysis of medical records of patients with tuberculosis admitted to the Internal Medicine Department of the University Clinics of Lubumbashi, located in the southeastern region of the Democratic Republic of the Congo, during the year 2019. Results: HIV-tuberculosis co-infection was identified in 37 out of 66 medical records reviewed (56.0%). Compared to HIV-negative patients, TB in HIV-positive individuals was more frequently observed in patients aged 40 years and older (56.8% vs. 34.4%, p = 0.004), in females (78.9% vs. 46.8%, p = 0.01), in cases of recurrent TB (37.8% vs. 27.5%), and in those with a history of diabetes mellitus (8.1% vs. 3.4%). Just over one-third of co-infected patients (37.4%) originated from the peripheral neighborhoods of the city of Lubumbashi, most of which are characterized by unfavorable socioeconomic conditions. Smear-negative forms of tuberculosis, lacking bacteriological confirmation, were predominant among co-infected patients (48.6% vs. 34.4%). Mortality rate at discharge was 13.5% among the co-infected patients. Mortality was associated with the following factors: smear-positive TB (21.0% vs. 5.5%), male sex (18.1% vs. 6.6%), diabetes mellitus (33.3% vs. 11.7%), and age over 40 years (19.0% vs. 6.2%). Conclusion: HIV-pulmonary tuberculosis co-infection is a frequent condition among inpatients at the University Clinics of Lubumbashi. The epidemiological and clinical profile is marked by the presence of factors that may adversely affect short-term prognosis.

Indexed as

CoinfectionHIV InfectionsTuberculosis, PulmonaryAdolescentAdultAgedAge FactorsCross-Sectional StudiesDemocratic Republic of the CongoFemaleHumansMaleMiddle AgedRecurrenceSex FactorsSocioeconomic FactorsHIVLubumbashipulmonary tuberculosis

Identifiers

PMID41064676
PMCPMC12500869

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.