ArticleThe Pan African medical journal2025
Epidemiological, pathological, and molecular characteristics of lung cancer in Casablanca, Morocco: a retrospective study.
Article in The Pan African medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Real-world data on oncology in Morocco: a narrative review of four decades of national evidence.Journal of cancer research and clinical oncology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: lung cancer remains a significant global health concern, responsible for the highest number of cancer-related deaths worldwide. In Morocco, it is the most prevalent cancer among men. This study aimed to describe the epidemiological characteristics of lung cancer and to explore the molecular profile of lung adenocarcinoma cases. Methods: a retrospective analysis was carried out over a 24-month period, from January 2020 to December 2021, at the Pathology Department of Ibn Rochd University Hospital in Casablanca, Morocco, encompassing 1,426 lung cancer cases. Statistical analyses were performed using GraphPad Prism 8 software. Results: our study reveals that the mean age was 59.9±12.06 years (median: 61 years, IQR: 54-67). A clear male predominance was observed in 75.9% (n=1,083). The most common histological type was adenocarcinoma, representing 49.6% (n=708). In adenocarcinoma cases, thyroid transcription factor-1 (TTF-1) expression was positive in 95.5% (n=469). Programmed death-ligand 1 (PD-L1) was mostly negative, with a tumor proportion score (TPS) <1% in 59.7% (n=83), 1-49% in 13.7% (n=19), and ≥50% in 26.6% (n=37). Anaplastic lymphoma kinase (ALK) expression was positive in only 4.1% (n=3) of cases. Epidermal growth factor receptor (EGFR) mutations were found in 22.2% (n=24), predominantly Ex19Del in 66.6% (n=16). All ALK-positive cases were PD-L1 negative (100%, n=3), while PD-L1 expression (TPS≥1%) was detected in 38.9% (n=7) of EGFR-mutated adenocarcinomas. Conclusion: this study characterizes lung adenocarcinoma as the predominant histological type, elucidates its principal molecular features and enables the determination of possible correlations between EGFR status, PD-L1 and ALK expression among Moroccan patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.