ArticleLaryngoscope investigative otolaryngology2025
Radiologic Evaluation of Paranasal Sinuses in Sickle Cell Anemia and Thalassemia: Case-Control Study.
Article in Laryngoscope investigative otolaryngology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Radiologic Evaluation of Paranasal Sinuses in Sickle Cell Anemia and Thalassemia: Case-Control Study.Laryngoscope investigative otolaryngology · 2025Article
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Authors and funding
9 authors.
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Abstract
Background: Sickle cell disease and thalassemia are inherited hematological disorders that are common worldwide. These patients suffer from chronic hemolytic anemia, which can result in bone marrow dysfunction and, in rare cases, extramedullary hematopoiesis. These pathophysiological changes can predispose patients to sinus complications or misdiagnosis in imaging studies. Objective: Evaluate the maxillary sinus abnormalities in patients with β-thalassemia, sickle cell anemia, and sickle cell-beta thalassemia. Methods: A multicenter, case-control study was conducted, including 212 participants, categorized into four groups: control ( Results: Significant maxillary sinus wall thickening across all disease groups was found, with the β-thalassemia exhibiting the most pronounced changes ( Conclusion: Our findings reveal significant maxillary sinus wall thickening in β-thalassemia, sickle cell anemia, and sickle cell-beta thalassemia. Recognizing these structural changes is important for radiologists and otolaryngologists, as they may resemble other pathologies and lead to diagnostic challenges if not carefully interpreted. Level of Evidence: 4.
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