Evidence map›Paper›PMID 41064527›Full record

ArticleFrontiers in bioengineering and biotechnology2025

A promising novel material-light-cured wound closure adhesives promote wound healing after pilonidal sinus open surgery: a Case Report.

Jiachun Ni, Yiheng Yang, Qinyuan Liu, Yu Deng, Renjie Zhou, Linyong Zhu, Ying Li, Zhenyi Wang, Changpeng Han

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Jiachun Ni *Department of Coloproctology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yiheng Yang *Department of Coloproctology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Qinyuan LiuDepartment of Coloproctology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yu DengDepartment of Coloproctology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Renjie ZhouSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Linyong ZhuSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Ying LiDepartment of Coloproctology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Zhenyi WangDepartment of Coloproctology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Changpeng HanDepartment of Coloproctology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/objectives: Pilonidal sinus disease (PSD), a common sacrococcygeal infectious disease, is characterized by sacrococcygeal swelling, pain, sacrococcygeal midline pits, sinus containing hair. Surgery is the main treatment for PSD. Although closure surgery reduces wound healing time, it has a high recurrence rate. Open surgery is the most effective procedure for treating PSD with reduced recurrence rates, but at the cost of large wounds, prolonged healing times, cumbersome care and long-term inactivity. Therefore, how to balance postoperative recurrence with prolonged wound healing time is a critical issue for clinicians. Herein, we introduced a novel material called light-cured wound closure adhesives, which is characterized by strong tissue binding strength, high biocompatibility, prominent wound healing capability. Methods: We present the case of a 22-year-old male with PSD who underwent open surgery. The light-cured wound closure adhesives were first applied to postoperative wound. We observed wound healing status, wound Numeric Rating Scale (NRS) pain scores, adverse events including exudation, infection, allergy, meanwhile documented the use of analgesics during follow-up period. Results: The wound healed at postoperative day 37, much shorter than that reported in the previous literature. The NRS pain scores are low. Adverse events includes excessive exudation, pruritus, granulation hyperplasia. Conclusion: Light-cured wound closure adhesives showed excellent pro-healing capabilities and brilliantly solved the paradox between high recurrence rate and prolonged wound healing time of PSD.

Indexed as

adhesivescase reportpilonidal sinussurgerywound healing

Identifiers

PMID41064527
PMCPMC12500601

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