ArticleFrontiers in medicine2025
Efficacy of bilateral quadratus lumborum block with liposomal bupivacaine for post-cesarean analgesia: a protocol for an open-label randomized controlled trial.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Anterior Quadratus Lumborum Block with Liposomal Bupivacaine versus Ropivacaine for Postoperative Recovery in Laparoscopic Colorectal Surgery: A Randomized Controlled Trial.Drug design, development and therapy · 2026Trial
- Effect of single-injection thoracic paravertebral block with liposomal bupivacaine on the quality of recovery after thoracic surgery: a protocol for an open-label, randomized controlled trial.Frontiers in medicine · 2025Article
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Authors and funding
6 authors.
Funding
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Abstract
Background: Effective postoperative pain management is essential for optimizing maternal comfort and recovery following cesarean delivery. However, achieving adequate analgesia remains a challenge due to suboptimal pain control and medication-related adverse effects. This study aims to evaluate the efficacy of bilateral quadratus lumborum block using liposomal bupivacaine for post-cesarean analgesia. Methods: This single-center, open-label, randomized controlled trial will enroll 201 adult parturients undergoing lower segment transverse cesarean section. Participants will be randomized in a 1:1:1 ratio into three groups ( Discussion: This study aims to provide high-quality evidence on the efficacy of bilateral single-injection quadratus lumborum block with liposomal bupivacaine, compared with standard intravenous analgesia alone and combined with quadratus lumborum block using ropivacaine. Ethics and dissemination: Ethics approval was obtained from the Ethics Committee of the Affiliated Hospital of Qingdao University (QYFYEC2024-297). All parturients will provide written informed consent. The results of this study will be published in a peer-reviewed journal. Clinical trial registration: Identifier ChiCTR2500095835.
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