Evidence map›Paper›PMID 41064507›Full record

ArticleFrontiers in medicine2025

Comparison of the effectiveness of vitrectomy with silicone oil or perfluoropropane tamponade for myopic foveoschisis with foveal detachment.

Handong Dan, Dongdong Wang, Zixu Huang, Yizong Liu, Huiming Hou, Yujia Jin, Zongming Song

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Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Handong DanHenan Eye Hospital, Henan Eye Institute, Henan Provincial People's Hospital, Henan Provincial People's Clinical Medical School of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China.
Dongdong WangHenan Eye Hospital, Henan Eye Institute, Henan Provincial People's Hospital, Henan Provincial People's Clinical Medical School of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China.
Zixu HuangHenan Eye Hospital, Henan Eye Institute, Henan Provincial People's Hospital, Henan Provincial People's Clinical Medical School of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China.
Yizong LiuHenan Eye Hospital, Henan Eye Institute, Henan Provincial People's Hospital, Henan Provincial People's Clinical Medical School of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China.
Huiming HouHenan Eye Hospital, Henan Eye Institute, Henan Provincial People's Hospital, Henan Provincial People's Clinical Medical School of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China.
Yujia JinHenan Eye Hospital, Henan Eye Institute, Henan Provincial People's Hospital, Henan Provincial People's Clinical Medical School of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China.
Zongming SongHenan Eye Hospital, Henan Eye Institute, Henan Provincial People's Hospital, Henan Provincial People's Clinical Medical School of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Vitrectomy with silicone oil or perfluoropropane (C3F8) tamponade is a standard of treatment for myopic foveoschisis with foveal detachment (MFFD). In this study, we compared the pre- and postoperative best-corrected visual acuity (BCVA) and maximum foveal thickness (MaxFT) of patients with MFFD who underwent vitrectomy with silicone oil or C3F8 tamponade. Methods: All patients underwent comprehensive ophthalmological examinations, including measurement of BCVA, axial measurement, optometry, intraocular pressure, slit-lamp examination, fundus examination, and optical coherence tomography. Patients with MFFD were divided into two groups. All patients underwent with 23-gauge pars plana vitrectomy with fovea-sparing internal limiting membrane peeling, and fluid-air exchange. One group underwent tamponade with silicone oil, whereas the other group underwent tamponade with C3F8. The silicone oil was completely removed upon complete resolution of MFFD. Phacoemulsification with intraocular lens implantation was performed when a lens opacity was noted during vitrectomy or along with silicone oil removal. BCVA and MaxFT were assessed at 1, 3, 6, and 12-months post-operatively. Patients with silicone oil were additionally assessed 3-months after silicone oil removal. All data were calculated using GraphPad Prism. Results: Forty-one patients with 41 eyes were enrolled in the study. Eighteen eyes were included in the silicone oil group, whereas 23 eyes were included in the C3F8 group. Both groups demonstrated significant improvement in BCVA and MaxFT at 1, 3, 6, and 12-months post-operatively. There was no significant difference in BCVA and MaxFT between both groups post-operatively. Transient ocular hypertension was noted in six and three cases in the silicone oil and C3F8 groups, respectively. One case in the C3F8 group developed a macular hole. There were no other complications in the two groups. Conclusion: Vitrectomy with fovea-sparing internal limiting membrane peeling, and silicone oil or C3F8 tamponade are effective and practical treatment options for MFFD.

Indexed as

foveal detachmentfovea-sparing internal limiting membrane peelingmyopic foveoschisispars plana vitrectomyperfluoropropane tamponadesilicone oil tamponade

Identifiers

PMID41064507
PMCPMC12500636

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.